C
Cécile Lebrand
Researcher at University of Lausanne
Publications - 30
Citations - 3844
Cécile Lebrand is an academic researcher from University of Lausanne. The author has contributed to research in topics: Serotonin & Guidepost cells. The author has an hindex of 24, co-authored 30 publications receiving 3612 citations. Previous affiliations of Cécile Lebrand include Massachusetts Institute of Technology & École Polytechnique.
Papers
More filters
Journal ArticleDOI
Separation and Characterization of Late Endosomal Membrane Domains
Toshihide Kobayashi,Toshihide Kobayashi,Marie-Hélène Beuchat,Julien Chevallier,Asami Makino,Nathalie Mayran,Jean-Michel Escola,Cécile Lebrand,Pierre Cosson,Tetsuyuki Kobayashi,Jean Gruenberg +10 more
TL;DR: The membrane composition of late endosomes by suborganellar fractionation in the absence of detergent is analyzed and it is found that the internal membranes of this multivesicular organelle can be separated from the limiting membrane and that each membrane population exhibited a defined composition.
Journal ArticleDOI
Late endosome motility depends on lipids via the small GTPase Rab7.
Cécile Lebrand,Michela Corti,Holly V. Goodson,Holly V. Goodson,Pierre Cosson,Valeria Cavalli,Nathalie Mayran,Julien Fauré,Jean Gruenberg +8 more
TL;DR: It is concluded that motor functions can be regulated by the membrane lipid composition via the Rab7 cycle, and that Rab7 in turn controls the net movement of late endocytic elements.
Journal ArticleDOI
Transient Uptake and Storage of Serotonin in Developing Thalamic Neurons
Cécile Lebrand,Olivier Cases,Christine Adelbrecht,Anne Doye,Chantal Alvarez,Salah El Mestikawy,Isabelle Seif,Patricia Gaspar +7 more
TL;DR: It is shown that the dense transient 5-HT innervation of the somatosensory, visual, and auditory cortices originates in the thalamus rather than in the raphe, which means internalized 5- HT might be stored and used as a "borrowed transmitter" for extraneuronal signaling or could exert an intraneuronal control on thalamic maturation.
Critical Role of Ena/VASP Proteins for Filopodia Formation in Neurons and in Function Downstream of Netrin-1
Cécile Lebrand,Lorene M. Lanier,Matthias Krause,Tatyana Svitkina,Gary G. Borisy,Erik W. Dent,Geraldine A. Strasser,Frank B. Gertler +7 more
TL;DR: It is proposed that Ena/VASP proteins control filopodial dynamics in neurons by remodeling the actin network in response to guidance cues.
Journal ArticleDOI
Critical Role of Ena/VASP Proteins for Filopodia Formation in Neurons and in Function Downstream of Netrin-1
Cécile Lebrand,Erik W. Dent,Geraldine A. Strasser,Lorene M. Lanier,Matthias Krause,Tatyana Svitkina,Gary G. Borisy,Frank B. Gertler +7 more
TL;DR: In this article, the authors found that Ena/VASP proteins play a pivotal role in formation and elongation of filopodia along neurite shafts and growth cone.