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Cecilie Bo Hansen
Researcher at Copenhagen University Hospital
Publications - 37
Citations - 561
Cecilie Bo Hansen is an academic researcher from Copenhagen University Hospital. The author has contributed to research in topics: Medicine & Antibody. The author has an hindex of 6, co-authored 21 publications receiving 169 citations. Previous affiliations of Cecilie Bo Hansen include University of Copenhagen.
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Journal ArticleDOI
Comparison of 16 Serological SARS-CoV-2 Immunoassays in 16 Clinical Laboratories.
Lene Holm Harritshøj,Mikkel Gybel-Brask,Shoaib Afzal,Shoaib Afzal,Pia R. Kamstrup,Charlotte Sværke Jørgensen,Marianne Kragh Thomsen,Linda Hilsted,Lennart Friis-Hansen,Pal B. Szecsi,Lise Pedersen,Lene Nielsen,Cecilie Bo Hansen,Peter Garred,Peter Garred,Trine-Line Korsholm,Susan Mikkelsen,Kirstine O. Nielsen,Bjarne Kuno Møller,Anne Tybjaerg Hansen,Kasper Iversen,Pernille B Nielsen,Rasmus Bo Hasselbalch,Kamille Fogh,Jakob B Norsk,Jonas H Kristensen,Kristian Schønning,Nikolai Kirkby,Alex C. Y. Nielsen,Lone H. Landsy,Mette Loftager,Dorte Kinggaard Holm,Anna Christine Nilsson,Susanne Gjørup Sækmose,Birgitte Grum-Schwensen,Bitten Aagaard,Thøger Gorm Jensen,Thøger Gorm Jensen,Dorte M. Nielsen,Henrik Ullum,Henrik Ullum,Henrik Ullum,Ram Benny Dessau +42 more
TL;DR: In this paper, the authors evaluated 15 commercial and one in-house anti-SARS-CoV-2 assays in 16 laboratories and achieved a specificity of ≥ 99% for all total-Ab and IgG assays except one, DiaSorin Liaison XL IgG (97.2%).
Journal ArticleDOI
SARS-CoV-2 Antibody Responses Are Correlated to Disease Severity in COVID-19 Convalescent Individuals.
Cecilie Bo Hansen,Ida Jarlhelt,Laura Pérez-Alós,Lone H. Landsy,Mette Loftager,Anne Rosbjerg,Charlotte Helgstrand,Jais Rose Bjelke,Thomas Egebjerg,Joseph G. Jardine,Charlotte Sværke Jørgensen,Kasper Iversen,Rafael Bayarri-Olmos,Peter Garred,Mikkel-Ole Skjoedt +14 more
TL;DR: It is shown that the IgM, A, and G Ab responses against receptor-binding domain are significantly correlated to the disease severity, and these assays and the data generated from them are highly relevant for diagnostics and prognostics and contribute to the understanding of long-term COVID-19 immunity.
Journal ArticleDOI
Modeling of waning immunity after SARS-CoV-2 vaccination and influencing factors
Laura Pérez-Alós,Jose Juan Almagro Armenteros,Johannes R. Madsen,Cecilie Bo Hansen,Ida Jarlhelt,Sebastian Rask Hamm,Line Dam Heftdal,Mia Pries-Heje,Dina Leth Møller,Kamille Fogh,Rasmus Bo Hasselbalch,Anne Rosbjerg,Søren Brunak,E. Sørensen,Margit Hørup Larsen,Sisse R. Ostrowski,Ruth Frikke-Schmidt,Rafael Bayarri-Olmos,Linda Hilsted,Kasper Iversen,Henning Bundgaard,Susanne Dam Nielsen,Peter Garred +22 more
TL;DR: In this paper , the authors examined antibody levels and T-cell gamma-interferon release after two doses of BNT162b2 vaccine or a combination of ChAdOx1-nCoV19 and BNT 162b2 vaccines for up to 230 days after the first dose.
Journal ArticleDOI
SARS-CoV-2 Antibodies Mediate Complement and Cellular Driven Inflammation.
Ida Jarlhelt,Sif Kaas Nielsen,Camilla Xenia Holtermann Jahn,Cecilie Bo Hansen,Laura Pérez-Alós,Anne Rosbjerg,Rafael Bayarri-Olmos,Mikkel-Ole Skjoedt,Mikkel-Ole Skjoedt,Peter Garred +9 more
TL;DR: In this article, the authors determined the distribution of IgG subclasses and complement activation levels in plasma from convalescent individuals using in-house developed ELISAs and found that increased classical complement activation was highly associated with COVID-19 disease severity.
Journal ArticleDOI
The Levels of the Lectin Pathway Serine Protease MASP-1 and Its Complex Formation with C1 Inhibitor Are Linked to the Severity of Hereditary Angioedema
Cecilie Bo Hansen,Dorottya Csuka,Lea Munthe-Fog,Lilian Varga,Henriette Farkas,Karin Møller Hansen,Claus Koch,Karsten Skjødt,Peter Garred,Mikkel-Ole Skjoedt +9 more
TL;DR: The results suggest that MASP-1 may exert a previously unrecognized role in the pathophysiology of HAE, and it is shown that MASp-1/C1-INH complexes circulate in normal human blood.