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Charlotte Sværke Jørgensen

Researcher at Statens Serum Institut

Publications -  87
Citations -  1877

Charlotte Sværke Jørgensen is an academic researcher from Statens Serum Institut. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 23, co-authored 67 publications receiving 1359 citations.

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Evaluation of nine commercial SARS-CoV-2 immunoassays

TL;DR: This study evaluated the sensitivity and specificity of nine commercially available serological tests and found that three enzyme-linked immunosorbent assays (ELISAs) and six point-of-care (POC) lateral flow tests showed 100% specificity.
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SARS-CoV-2 Antibody Responses Are Correlated to Disease Severity in COVID-19 Convalescent Individuals.

TL;DR: It is shown that the IgM, A, and G Ab responses against receptor-binding domain are significantly correlated to the disease severity, and these assays and the data generated from them are highly relevant for diagnostics and prognostics and contribute to the understanding of long-term COVID-19 immunity.
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Non-specific binding in solid phase immunoassays for autoantibodies correlates with inflammation markers.

TL;DR: It is proposed that non-specific binding may be interpreted as an informative finding indicative of elevated IgG and inflammation, and shown that the level of non- specific binding correlates with the IgG concentration and therefore is shown to be indicative of inflammation.