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Cedric S. Raine
Researcher at Albert Einstein College of Medicine
Publications - 296
Citations - 27558
Cedric S. Raine is an academic researcher from Albert Einstein College of Medicine. The author has contributed to research in topics: Myelin & Multiple sclerosis. The author has an hindex of 82, co-authored 296 publications receiving 26593 citations. Previous affiliations of Cedric S. Raine include Yeshiva University & Icahn School of Medicine at Mount Sinai.
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Journal ArticleDOI
Homing of T cells to the central nervous system throughout the course of relapsing experimental autoimmune encephalomyelitis in Thy-1 congenic mice
TL;DR: This is the first study showing unequivocally the presence of MBP-stimulated, adoptively transferred T cells within the CNS of recipients throughout the course of EAE, particularly during later relapsing stages, indicating that the persistent presence of antigen-specific T cells may be required for the recruitment of non-CNS antigen-responsive immune cells.
Journal Article
Induction of oligodendrocyte proliferation and remyelination after chronic demyelination. Relevance to multiple sclerosis.
TL;DR: Observations from multiple sclerosis lesions showed that oligodendrocyte proliferation and CNS remyelination occur in human subcortical white matter, but to a lesser degree than that seen in the CNS of MBP/GC/treated guinea pigs.
Journal ArticleDOI
Axon diameter and myelin thickness. Unusual relationships in dorsal root ganglia.
TL;DR: Peripheral nerve fibers close to the sensory neurons of dorsal root ganglia displayed unusually thin myelin sheaths in relation to their axon diameter, indicating that other, unknown factors are operative in the control of myelination.
Journal ArticleDOI
Age Dependence of Clinical and Pathological Manifestations of Autoimmune Demyelination: Implications for Multiple Sclerosis
Mary E. Smith,Nancy L. Eller,Nancy L. Eller,Henry F. McFarland,Michael K. Racke,Michael K. Racke,Cedric S. Raine +6 more
TL;DR: Age-related resistance to clinical EAE in developing mice is reminiscent of an age-related characteristic of MS previously difficult to study in vivo, and may allow study of factors associated with the known occasional poor correlation of CNS inflammation and demyelination and clinical changes in this disease.
Book ChapterDOI
Morphological Aspects of Myelin and Myelination
TL;DR: Myelin is morphologically unique, and, while the present section will highlight this uniqueness, it is important to note that myelin is also distinct biochemically, physiologically, and immunologically.