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Chang-Lun Shao

Researcher at Ocean University of China

Publications -  233
Citations -  5271

Chang-Lun Shao is an academic researcher from Ocean University of China. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 34, co-authored 217 publications receiving 3976 citations. Previous affiliations of Chang-Lun Shao include Chinese Ministry of Education & Sun Yat-sen University.

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Structures and Absolute Configurations of Diketopiperazine Alkaloids Chrysopiperazines A⁻C from the Gorgonian-Derived Penicillium chrysogenum Fungus.

TL;DR: The absolute configurations of C-19 in 1 and 3, which was very challenging to be identified due to the flexible conformation in a short aliphatic chain, were successfully determined by the vibrational circular dichroism (VCD) method.
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Sorbicillinoid Derivatives From Sponge-Derived Fungus Trichoderma reesei (HN-2016-018).

TL;DR: Six new sorbicillinoid structures including absolute configurations were elucidated by analysis of NMR, MS data, and calculated ECD spectra, together with three known analogs, trichodimerol (6), 24-hydroxy-bisvertinol (8), and bisverts (9), were isolated from the sponge-derived fungus Trichoderma reesei.
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Microketides A and B, Polyketides from a Gorgonian-Derived Microsphaeropsis sp. Fungus

TL;DR: Two new C-11 epimeric polyketides were obtained from the gorgonian-derived fungus Microsphaeropsis sp.
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(+)- and (-)-Pestaloxazine A, a Pair of Antiviral Enantiomeric Alkaloid Dimers with a Symmetric Spiro[oxazinane-piperazinedione] Skeleton from Pestalotiopsis sp.

TL;DR: A pair of enantiomeric alkaloid dimers, (+)- and (−)-pestaloxazine A (1), with an unprecedented symmetric spiro[oxazinane-piperazinedione] skeleton, consisting of 22 carbons and 12 heteroatoms, were isolated from a Pestalotiopsis sp. fungus derived from a soft coral as mentioned in this paper.
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Structure modification, antialgal, antiplasmodial, and toxic evaluations of a series of new marine-derived 14-membered resorcylic acid lactone derivatives

TL;DR: Combining evaluation of chemical ecology with pharmacological models will be implemented as a systematic strategy, not only for environmentally friendly antifoulants but also for structurally novel drugs.