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Chang-Lun Shao

Researcher at Ocean University of China

Publications -  233
Citations -  5271

Chang-Lun Shao is an academic researcher from Ocean University of China. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 34, co-authored 217 publications receiving 3976 citations. Previous affiliations of Chang-Lun Shao include Chinese Ministry of Education & Sun Yat-sen University.

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Co-cultivation With 5-Azacytidine Induced New Metabolites From the Zoanthid-Derived Fungus Cochliobolus lunatus.

TL;DR: It could be concluded that chemical epigenetic agents could induce C. lunatus to produce new types of secondary metabolites differing from its original products (RALs), including α-pyrone compounds with the epoxy ring or bromine atom on the seven-numbered side chain.
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Chemical and Bioactive Marine Natural Products of Coral-Derived Microorganisms (2015-2017)

TL;DR: This work reviewed the natural products reported from 2015 to 2017 that have a wide range of bioactivities against different biological targets and exhibited in vitro or in vivo activities against tumor cell lines, parasites, pathogenic bacteria, fungi and virus.
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Cytotoxic Nitrobenzoyloxy-substituted Sesquiterpenes from Spongederived Endozoic Fungus Aspergillus insulicola MD10-2.

TL;DR: Five nitrobenzoyloxy-substituted sesquiterpenes 1-5 were isolated from the culture mycelia of an endozoic fungus Aspergillus insulicola MD10-2, obtained from the South China Sea sponge Cinachyrella australiensis, suggesting the double bond at C-7 had an effect on cytotoxic activity as well.
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Cytotoxic scalarane sesterterpenoids from the South China Sea sponge Carteriospongia foliascens

TL;DR: Eleven new scalarane sesterterpenoids, including three 20,24-bishomo-25-norscalaranes, carteriofenones A–C (1–3), and eight 20, 24-bishomoscalarane, carTERiofenone D–K (4–11), along with two known analogues, were obtained from the marine sponge Carteriospongia foliascens collected from the South China Sea.
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Two new metabolites from the Hainan soft coral Sarcophyton crassocaule

TL;DR: Two new metabolites have been isolated from the Hainan soft coral Sarcophyton crassocaule and their structures were elucidated on the basis of a detailed analysis of spectroscopic data, and by comparison of their NMR spectral data with those of the related model compounds.