Chang-Lun Shao

TL;DR: In this paper, eight natural isocoumarins (1-8) were isolated from a marine-derived Exserohilum sp. fungus and a small library of 22 new derivatives (1a-1n, 2a, 3a-3c, 4a-4c, and 7a) were semisynthesized by varying the substituents of the aromatic ring and the aliphatic side chains.

TL;DR: The preliminarily investigated pharmacokinetics of AIH was investigated preliminarily by ultra-performance liquid chromatography coupled with triple quadrupole mass spectrometry (UPLC-MS/MS) and may provide a basis for the elucidation of the pharmacokinetic characteristics of bioactive components from AIH.

TL;DR: One new δ-valerolactone and one new natural phenolic glycoside 2, together with four known compounds 3–6, were isolated from the fruits of Ligustrum lucidum and their structures were elucidated on the basis of spectral data.

TL;DR: In this article, the authors used the National Natural Science Foundation of China (Nos. 40976077; 30901879), the Research Fund for the Doctoral Program of Higher Education, Ministry of Education of China, No. 20090132110002), the Basic Research Program of Science and Technology, Ministry Of Science and technology of China(No. 2007FY210500), and the Program for Changjiang Scholars and Innovative Research Team in University.

TL;DR: In this paper, a mixed nanomicelles based on TPGS and F127 copolymers (M-BFA) was used to encapsulate Macrolide brefeldin A (BFA), which is a well-known lead compound in cancer chemotherapy, with poor solubility and instability.