Changjiang Huang

TL;DR: This is the first study to define uptake kinetics and to focus on behavioral consequences following PFOS exposure in zebrafish, and further the understanding of the toxicity of PFOS to aquatic organisms and suggest the need for additional research to identify the mode ofPFOS toxicity.

TL;DR: Larval zebrafish phenotypic assay is a highly predictive animal model for rapidly in vivo assessment of compound hepatot toxicity and can serve as an intermediate step between cell-based evaluation and conventional animal testing of hepatotoxicity.

TL;DR: Compared to conventional mammal testing, zebrafish testing for assessing developmental and reproductive toxicity offers several compelling experimental advantages, including transparency of embryo and larva, higher throughput, shorter test period, lower cost, smaller amount of compound required, easier manipulation and direct compound delivery.

TL;DR: This study provides the first evidence that parental exposure to environmentally relevant concentrations of PBDEs could cause adverse effects on neurodevelopment in zebrafish offspring.

TL;DR: The general observation of elevated PAH concentrations in all matrix suggests a possible contribution by the local leather industry on the PAH concentration in the Aojiang watershed.