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Changqi C. Zhu

Researcher at Ferris State University

Publications -  12
Citations -  985

Changqi C. Zhu is an academic researcher from Ferris State University. The author has contributed to research in topics: Homeobox & Drosophila melanogaster. The author has an hindex of 10, co-authored 10 publications receiving 922 citations. Previous affiliations of Changqi C. Zhu include University of Minnesota & St. Jude Children's Research Hospital.

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Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development

TL;DR: It is demonstrated that regionalization of the vertebrate forebrain involves repression of Wnt1 expression by Six3 within the anterior neuroectoderm, and this results support the hypothesis that a Wnt signal gradient specifies posterior fates in the anterior neural plate.
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Six3-mediated auto repression and eye development requires its interaction with members of the Groucho-related family of co-repressors.

TL;DR: It is reported that Grg4 and Grg5, mouse counterparts of the Drosophila transcriptional co-repressor Groucho, interact with mouse Six3 and its closely related member Six6, which may also be involved in vertebrate eye development.
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Six3 promotes the formation of ectopic optic vesicle‐like structures in mouse embryos

TL;DR: It is shown that similar to Drosophila, where the eyeless/Pax6 gene regulates the eye‐specific expression of so, Six3 expression in the murine lens placodal ectoderm is also controlled by Pax6.
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Midgut-Derived Activin Regulates Glucagon-like Action in the Fat Body and Glycemic Control.

TL;DR: It is demonstrated that Activin-β (Actβ), an activin ligand predominantly produced in the enteroendocrine cells of the midgut, is upregulated by chronic high-sugar diet and signals through Babo to promote AKH action in the fat body, leading to hyperglycemia.
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Expression of androgen receptor mRNA during mouse embryogenesis

TL;DR: It is demonstrated that AR transcripts occur in the developing external genitalia, pituitary, adrenals, kidneys and musculus levator ani, in addition to the known expression sites in the Wolffian ducts and its derivatives and during development of the mammary glands.