L
Luis Puelles
Researcher at University of Murcia
Publications - 280
Citations - 21643
Luis Puelles is an academic researcher from University of Murcia. The author has contributed to research in topics: Forebrain & Neural plate. The author has an hindex of 71, co-authored 269 publications receiving 19858 citations. Previous affiliations of Luis Puelles include University of Alicante & University of Seville.
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Journal ArticleDOI
Cortical Excitatory Neurons and Glia, But Not GABAergic Neurons, Are Produced in the Emx1-Expressing Lineage
Jessica A. Gorski,Tiffany Talley,Mengsheng Qiu,Luis Puelles,John L.R. Rubenstein,Kevin R. Jones +5 more
TL;DR: A strain of mice is generated that expresses the Cre recombinase in a spatial and temporal pattern like that observed for Emx1, and it is demonstrated that radial glia, Cajal-Retzius cells, glutamatergic neurons, astrocytes, and oligodendrocytic cells of most pallial structures originate from an EmX1-expressing lineage.
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Pallial and subpallial derivatives in the embryonic chick and mouse telencephalon, traced by the expression of the genes Dlx-2, Emx-1, Nkx-2.1, Pax-6, and Tbr-1
Luis Puelles,Ellen Kuwana,Eduardo Puelles,Alessandro Bulfone,Kenji Shimamura,Jerry Keleher,Susan Smiga,John L.R. Rubenstein +7 more
TL;DR: Differences in the expression topography of Tbr‐1 and Emx‐1 suggest the existence of a novel “ventral pallium” subdivision, which is an EmX‐1‐negative pallial territory intercalated between the striatum and the lateral pallium.
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Expression patterns of homeobox and other putative regulatory genes in the embryonic mouse forebrain suggest a neuromeric organization
TL;DR: A neuromeric model of the forebrain is described that is consistent with the expression patterns of these genes, and that provides a framework for understanding the morphological relationships within this complex structure.
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Forebrain gene expression domains and the evolving prosomeric model
TL;DR: This work sketches a simplified model, in which the secondary prosencephalon is a complex protosegment not subdivided into prosomeres, which exhibits patterning singularities, and continues to postulate that Prosomeres p1-p3 are the caudal forebrain.
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Longitudinal organization of the anterior neural plate and neural tube
TL;DR: In this paper, the authors describe studies of the expression of several genes in the mouse between 7.5 and 10.5 days post coitum (dpc) that provide evidence for the trajectory of the anterior-posterior axis and the longitudinal organization of the CNS, and demonstrate that the earliest longitudinal axon pathways of the forebrain are spatially correlated with the longitudinal domain defined by Nkx-2.2.