C
Chao Xing
Researcher at University of Texas Southwestern Medical Center
Publications - 206
Citations - 11484
Chao Xing is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Medicine & Gene. The author has an hindex of 38, co-authored 169 publications receiving 8895 citations. Previous affiliations of Chao Xing include Case Western Reserve University & Bristol-Myers Squibb.
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Journal ArticleDOI
A Varying Coefficient Model to Jointly Test Genetic and Gene–Environment Interaction Effects
Journal ArticleDOI
Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs’ Endothelial Corneal Dystrophy
Brian C. Leonard,Sangwan Park,Soohyun Kim,Laura J. Young,Iman Jalilian,K. Cosert,Xunzhi Zhang,Jessica M. Skeie,Hanna Shevalye,Vanessa Rozo,Xin Gong,Chao Xing,Christopher J. Murphy,Mark A. Greiner,Venkateswara Mootha,Vijay Krishna Raghunathan,Sara M Thomasy +16 more
TL;DR: In this paper , the role of Wwtr1 in murine ocular structure and function and determination of mechanotransduction in Fuchs' endothelial corneal dystrophy (FECD) was defined.
Posted ContentDOI
A fast-killing tyrosine amide ((S)-SW228703) with blood and liver-stage antimalarial activity associated with the Cyclic Amine Resistance Locus (PfCARL)
Leah S. Imlay,Aloysus K. Lawong,Suraksha Gahalawat,Ashwani Kumar,Chao Xing,Nimisha Mittal,Sergio Wittlin,Alisje Churchyard,Hanspeter Niederstrasser,Benigno Crespo-Fernández,Bruce A. Posner,Francisco-Javier Gamo,Jake Baum,Elizabeth A. Winzeler,Benoît Laleu,Joseph M. Rey,Margaret A. Phillips +16 more
TL;DR: (S)-SW703 provides a new chemical series with broad activity on multiple life-cycle stages and a fast-killing mechanism of action, available for lead optimization to generate new treatments for malaria.
Journal ArticleDOI
A Novel Syndrome With Short Stature, Mandibular Hypoplasia, and Osteoporosis May Be Associated With a PRRT3 Variant.
Abhimanyu Garg,Hatem El-Shanti,Hatem El-Shanti,Chao Xing,Zhengyang Zhou,Mousa Abujbara,Khadeja Al-Rashed,Mohammed El-Khateeb,Kamel Ajlouni,Anil K. Agarwal +9 more
TL;DR: It is concluded that the homozygous p.Glu394Lys variant in PRRT3 may be associated with a novel autosomal recessive, progeroid syndrome with short stature, mandibular hypoplasia, osteoporosis, short eyebrows, and mild growth hormone (GH) deficiency.
Journal ArticleDOI
22q11.2 Deletion Syndrome Causes a Thymus Hypoplasia Corrected by Mesenchymal Cell Replacement
Nicolai S. C. van Oers,Pratibha Bhalla,Angela Moses,Ashwani Kumar,Chao Xing,Christian A. Wysocki,Ondine Cleaver,M. Louise Markert,M. Teresa de la Morena +8 more
TL;DR: In this article , the authors compared the development of the thymus in embryos from various 22q11.2 deletion syndrome mouse models, normal controls and Foxn1 mutant mice.