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Chaoyong Yang
Researcher at Xiamen University
Publications - 114
Citations - 3725
Chaoyong Yang is an academic researcher from Xiamen University. The author has contributed to research in topics: Aptamer & Systematic evolution of ligands by exponential enrichment. The author has an hindex of 24, co-authored 114 publications receiving 1781 citations. Previous affiliations of Chaoyong Yang include Shanghai Jiao Tong University.
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Journal ArticleDOI
Discovery of Aptamers Targeting the Receptor-Binding Domain of the SARS-CoV-2 Spike Glycoprotein.
Yanling Song,Jia Song,Xinyu Wei,Mengjiao Huang,Miao Sun,Lin Zhu,Bingqian Lin,Haicong Shen,Zhi Zhu,Chaoyong Yang,Chaoyong Yang +10 more
TL;DR: This study identified high-binding-affinity aptamers targeting SARS-CoV-2 RBD, using an ACE2 competition-based aptamer selection strategy and a machine learning screening algorithm, and suggests that two aptamer may have partially identical binding sites at ACE2 on Sars- coV- 2 RBD.
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Aptamer-Based Detection of Circulating Targets for Precision Medicine.
Lingling Wu,Yidi Wang,Xing Xu,Yilong Liu,Bingqian Lin,Mingxia Zhang,Jialu Zhang,Shuang Wan,Chaoyong Yang,Chaoyong Yang,Weihong Tan,Weihong Tan,Weihong Tan +12 more
TL;DR: A broad overview of aptamer-based liquid biopsy techniques for precision medicine can be found in this article, where the authors present a summary of state-of-the-art strategies for multivalent aptamer assembly and aptamer interface modification.
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Enrichment and single-cell analysis of circulating tumor cells
Yanling Song,Yanling Song,Tian Tian,Yuanzhi Shi,Wenli Liu,Yuan Zou,Tahereh Khajvand,Sili Wang,Zhi Zhu,Chaoyong Yang +9 more
TL;DR: This review aims to provide in-depth insights into CTC analysis, including various techniques for isolation of C TCs and single-cell analysis of CTCs, as well as current developmental trends and promising research directions.
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Design and Synthesis of Target-Responsive Aptamer-Cross-linked Hydrogel for Visual Quantitative Detection of Ochratoxin A
Rudi Liu,Yishun Huang,Yanli Ma,Shasha Jia,Mingxuan Gao,Jiuxing Li,Huimin Zhang,Dunming Xu,Min Wu,Yan Chen,Zhi Zhu,Chaoyong Yang +11 more
TL;DR: The integration of a target-responsive hydrogel with portable enrichment by IAC, as well as signal amplification and quantitative readout by a simple microfluidic device, offers a new method for portable detection of food safety hazard toxin OTA.
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Aptamer Blocking Strategy Inhibits SARS-CoV-2 Virus Infection.
Miao Sun,Siwen Liu,Xinyu Wei,Shuang Wan,Mengjiao Huang,Ting Song,Yao Lu,Xiaonan Weng,Zhu Lin,Honglin Chen,Yanling Song,Chaoyong Yang,Chaoyong Yang +12 more
TL;DR: In this paper, an aptamer blocking strategy was proposed by engineering aptamers' binding to the region on SRBD that directly mediates ACE2 receptor engagement, leading to block SARS-CoV-2 infection.