C
Charles C. Coddington
Researcher at Eastern Virginia Medical School
Publications - 39
Citations - 1840
Charles C. Coddington is an academic researcher from Eastern Virginia Medical School. The author has contributed to research in topics: Sperm & Zona pellucida. The author has an hindex of 19, co-authored 32 publications receiving 1780 citations. Previous affiliations of Charles C. Coddington include Tufts University & Tygerberg Hospital.
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Journal ArticleDOI
The hemizona assay (HZA): development of a diagnostic test for the binding of human spermatozoa to the human hemizona pellucida to predict fertilization potential * † ‡
Lani J. Burkman,Charles C. Coddington,Daniel R. Franken,Thinus F. Kruger,Zev Rosenwaks,Gary D. Hodgen +5 more
TL;DR: Sperm from fertile men exhibited significantly higher binding capacity to hemizonae compared with sperm from men who had fertilization failure during in vitro fertilization (IVF) treatment, demonstrating that the HZA may be a useful diagnostic tool in male infertility evaluations.
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Factors affecting fertilization: endometrial placental protein 14 reduces the capacity of human spermatozoa to bind to the human zona pellucida*†
TL;DR: Placental protein 14 produced a potent, fast, and dose-dependent inhibition of binding of human spermatozoa to the human ZP without affecting other prefertilization events (i.e., hyperactivated motility or AR); the detrimental effect on sperm-zona interaction seems to be specific for this endometrial epithelial protein.
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Evaluation of outpatient hysteroscopy, saline infusion hysterosonography, and hysterosalpingography in infertile women: a prospective, randomized study ☆
Samuel E Brown,Charles C. Coddington,John A. Schnorr,James P. Toner,William E. Gibbons,Sergio Oehninger +5 more
TL;DR: OHS, SIS, and HSG were statistically equivalent regarding evaluation of uterine cavity pathology in infertile women.
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The hemizona assay (HZA): a predictor of human sperm fertilizing potential in in vitro fertilization (IVF) treatment.
Daniel R. Franken,Sergio Oehninger,Lani J. Burkman,Charles C. Coddington,Thinus F. Kruger,Zev Rosenwaks,Anibal A. Acosta,Gary D. Hodgen +7 more
TL;DR: Assessment of the relationship between sperm binding to the hemizona and in vitro fertilization (IVF) success enhanced confidence that the HZA is diagnostic for identification of patients at high risk of failing to achieve fertilization in vitro.
Journal ArticleDOI
Hemizona assay: assessment of sperm dysfunction and prediction of in vitro fertilization outcome
Sergio Oehninger,Charles C. Coddington,Daniel A. Franken,Richard T. Scott,Lani J. Burkman,Anibal A. Acosta,Gary D. Hodgen +6 more
TL;DR: The authors conclude that the HZA is a valuable tool for evaluating dysfunctional sperm-zona pellucida binding, with good predictive value for fertilization in vitro.