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Charles H. Hennekens

Researcher at Boston University

Publications -  15
Citations -  1243

Charles H. Hennekens is an academic researcher from Boston University. The author has contributed to research in topics: Aspirin & Randomized controlled trial. The author has an hindex of 9, co-authored 15 publications receiving 1232 citations. Previous affiliations of Charles H. Hennekens include University of Queensland & United States Department of Veterans Affairs.

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Intake of trans fatty acids and risk of coronary heart disease arnong wornen

TL;DR: Intakes of foods that are major sources of trans isomers (margarine, cookies [biscuits], cake, and white bread) were each significantly associated with higher risks of CHD, supporting the hypothesis that consumption of partially hydrogenated vegetable oils may contribute to occurrence ofCHD.
Journal ArticleDOI

Analgesic use and change in kidney function in apparently healthy men.

TL;DR: In this paper, a prospective cohort study of 4,494 US male physicians who provided blood samples in both 1982 and 1996 showed increased creatinine levels in 242 participants and decreased glomerular filtration rate (GFR) in 224 participants.

ORIGINAL INVESTIGATIONS Pathogenesis and Treatment of Kidney Disease and Hypertension Analgesic Use and Change in Kidney Function in Apparently Healthy Men

TL;DR: Occasional to moderate analgesic intake of aspirin, acetaminophen, or NSAIDs does not appear to increase the risk for decline in kidney function during a period of 14 years, and was associated with a reduced risk for change in kidneys function in participants without cardiovascular risk factors.
Book

Clinical trials in cardiovascular disease : a companion to Braunwald's heart disease

TL;DR: This study presents a meta-analysis of 26 Randomized Trials investigating the impact of cholesterol reduction, postmenopausal Hormone Replacement Therapy, and other Dietary Interventions on the risk of heart disease and stroke in women over the course of a 12-month period.
Journal ArticleDOI

Effect of alternate-day regular and enteric-coated aspirin on platelet aggregation, bleeding time, and thromboxane A2 levels in bleeding-time blood.

TL;DR: Regular and enteric-coated aspirin preparations were equally efficacious in prolonging the bleeding time, inhibiting platelet aggregation, and suppressing thromboxane A2 production.