C
Charles Landis
Researcher at University of Washington
Publications - 14
Citations - 1677
Charles Landis is an academic researcher from University of Washington. The author has contributed to research in topics: Sofosbuvir & Liver transplantation. The author has an hindex of 6, co-authored 14 publications receiving 1577 citations. Previous affiliations of Charles Landis include Albert Einstein College of Medicine.
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Ledipasvir and Sofosbuvir Plus Ribavirin for Treatment of HCV Infection in Patients With Advanced Liver Disease
Michael Charlton,Gregory T. Everson,Steven L. Flamm,Princy Kumar,Charles Landis,Robert S. Brown,Michael W. Fried,Norah A. Terrault,Jacqueline G. O'Leary,Hugo E. Vargas,Alexander Kuo,Eugene R. Schiff,Mark S. Sulkowski,Richard Gilroy,Kymberly D. Watt,Kimberly A Brown,Paul Y. Kwo,Surakit Pungpapong,Kevin M. Korenblat,Andrew J. Muir,Lewis Teperman,Robert J. Fontana,Jill Denning,Sarah Arterburn,Hadas Dvory-Sobol,Theo S. Brandt-Sarif,Phillip S. Pang,John G. McHutchison,K. Rajender Reddy,Nezam H. Afdhal +29 more
TL;DR: The combination of ledipasvir, sofosbuvir, and ribavirin for 12 weeks produced high rates of SVR12 in patients with advanced liver disease, including those with decompensated cirrhosis before and after liver transplantation.
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Ledipasvir and Sofosbuvir Plus Ribavirin for Treatment of HCV Infection in Patients With Advanced Liver Disease
Michael Charlton,Gregory T. Everson,Steven L. Flamm,Princy Kumar,Charles Landis,Robert S. Brown,Michael W. Fried,Norah A. Terrault,Jacqueline G. O'Leary,Hugo E. Vargas,Alexander Kuo,Eugene R. Schiff,Mark S. Sulkowski,Richard Gilroy,Kymberly D. Watt,Kimberly A Brown,Paul Y. Kwo,Surakit Pungpapong,Kevin M. Korenblat,Andrew J. Muir,Lewis Teperman,Robert J. Fontana,Jill Denning,Sarah Arterburn,Hadas Dvory-Sobol,Theo S. Brandt-Sarif,Phillip S. Pang,John G. McHutchison,K. Rajender Reddy,Nezam H. Afdhal +29 more
TL;DR: In this article, the NS5A inhibitor ledipasvir, the nucleotide polymerase inhibitor sofosbuvir, and ribavirin were used to treat chronic hepatitis C virus (HCV) infection in patients with advanced liver disease.
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The hepatic stem cell niche: Identification by label‐retaining cell assay
Reiichiro Kuwahara,Alexander Kofman,Charles Landis,E. Scott Swenson,Els Barendswaard,Neil D. Theise +5 more
TL;DR: The results confirm several different and often contradictory lines of investigation regarding the intrahepatic location of stem/progenitor cells and suggest that the liver has a multi‐tiered, flexible system of regeneration rather than a single stem/ Progenitor cell location.
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Noninvasive evaluation of liver repopulation by transplanted hepatocytes using 31P MRS imaging in mice.
Charles Landis,Kosho Yamanouchi,H. Zhou,Sankar Mohan,Namita Roy-Chowdhury,David A. Shafritz,Alan P. Koretsky,Jayanta Roy-Chowdhury,Hoby P. Hetherington,Chandan Guha +9 more
TL;DR: This study combined a noninvasive imaging technique to assess donor hepatocyte proliferation with a preparative regimen of partial liver irradiation that allowed regional repopulation of the host liver.
Safety and efficacy of treatment with once-daily ledipasvir/sofosbuvir (90/400 mg) for 12 weeks in genotype 1 hcv-infected patients with severe renal impairment.
E.J. Lawitz,Charles Landis,Benedict Maliakkal,Maurizio Bonacini,Grisell Ortiz-Lasanta,Jiaxue Zhang,Erik Mogalian,Shampa De-Oertel,Anu Osinusi,D.M. Brainard,John G. McHutchison,Csm Yip,H.-C. Huang,Steven Flamm,Stuart C Gordon,E.J. Gane +15 more