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Charles Lassman

Researcher at University of California, Los Angeles

Publications -  88
Citations -  7898

Charles Lassman is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Liver transplantation & Transplantation. The author has an hindex of 43, co-authored 88 publications receiving 7323 citations. Previous affiliations of Charles Lassman include UCLA Medical Center.

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Effect of vessel size on creation of hepatic radiofrequency lesions in pigs: assessment of the "heat sink" effect.

TL;DR: There appears to be a narrow transition zone for hepatic vessels at 2-4 mm, beyond which the heat sink effect was seen consistently and substantial vascular injury was rare.
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Cutting Edge: TLR4 Activation Mediates Liver Ischemia/Reperfusion Inflammatory Response via IFN Regulatory Factor 3-Dependent MyD88-Independent Pathway

TL;DR: The results show that IFN regulatory factor 3, but not MyD88, mediated IRI-induced TLR4 activation leading to liver inflammation and hepatocellular damage.
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Liver transplantation criteria for hepatocellular carcinoma should be expanded: a 22-year experience with 467 patients at UCLA.

TL;DR: This largest single institution experience with OLT for HCC demonstrates prolonged survival after liver transplantation for tumors beyond Milan criteria but within UCSF criteria, both when classified by preoperative imaging and by explant pathology.