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Charles Thivolet

Researcher at Claude Bernard University Lyon 1

Publications -  133
Citations -  5992

Charles Thivolet is an academic researcher from Claude Bernard University Lyon 1. The author has contributed to research in topics: Diabetes mellitus & Type 1 diabetes. The author has an hindex of 39, co-authored 122 publications receiving 5212 citations. Previous affiliations of Charles Thivolet include University of Lyon & Necker-Enfants Malades Hospital.

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Cerebellar ataxia with anti-glutamic acid decarboxylase antibodies: study of 14 patients.

TL;DR: A link between high level of GAD-Ab and some cases of cerebellar ataxia, particularly women with IDDM is suggested, and the cerebrospinal fluid should be evaluated for the presence of oligoclonal IgG bands and intrathecal synthesis of GADS to further prove an autoimmune origin of the syndrome.
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Mesenchymal stem cells protect NOD mice from diabetes by inducing regulatory T cells.

TL;DR: MSCs prevent autoimmune beta cell destruction and subsequent diabetes by inducing regulatory T cells and may offer a novel cell-based approach for the prevention of autoimmune diabetes and for islet cell transplantation.
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A cholera toxoid-insulin conjugate as an oral vaccine against spontaneous autoimmune diabetes

TL;DR: Protection against autoimmune diabetes can be achieved by feeding minute amounts of a pancreas islet cell autoantigen linked to CTB and appears to involve the selective migration and retention of protective T cells into lymphoid tissues draining the site of organ injury.