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Chayanon Peerapittayamongkol
Researcher at Mahidol University
Publications - 12
Citations - 334
Chayanon Peerapittayamongkol is an academic researcher from Mahidol University. The author has contributed to research in topics: Single-nucleotide polymorphism & Fetal hemoglobin. The author has an hindex of 6, co-authored 10 publications receiving 300 citations.
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Journal ArticleDOI
A genome-wide association identified the common genetic variants influence disease severity in β0-thalassemia/hemoglobin E
Manit Nuinoon,Wattanan Makarasara,Taisei Mushiroda,Iswari Setianingsih,Pustika Amalia Wahidiyat,Orapan Sripichai,Natsuhiko Kumasaka,Atsushi Takahashi,Saovaros Svasti,Thongperm Munkongdee,Surakameth Mahasirimongkol,Chayanon Peerapittayamongkol,Vip Viprakasit,Naoyuki Kamatani,Pranee Winichagoon,Michiaki Kubo,Yusuke Nakamura,Suthat Fucharoen +17 more
TL;DR: It is revealed that all the three reported loci and the α-globin gene locus are the best and common predictors of the disease severity in β-thalassemia.
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Genome-wide linkage scan and association study of PARL to the expression of LHON families in Thailand
Nopasak Phasukkijwatana,Bussaraporn Kunhapan,Jim Stankovich,Jim Stankovich,Wanicha Chuenkongkaew,Russell Thomson,Timothy A. Thornton,Melanie Bahlo,Taisei Mushiroda,Yusuke Nakamura,Surakameth Mahasirimongkol,Aung Win Tun,Chatchawan Srisawat,Chanin Limwongse,Chayanon Peerapittayamongkol,Thanyachai Sura,Wichit Suthammarak,Patcharee Lertrit +17 more
TL;DR: A genome-wide linkage scan with 400 microsatellite markers in 9 large Thai LHON G11778A pedigrees showed the most evidence of association between two SNPs, rs3749446 and rs1402000, located in PARL presenilins-associated rhomboid-like and LHON expression, which has long been believed to intrigue the neurodegeneration of LHON.
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Protective effect of mangosteen extract against beta-amyloid-induced cytotoxicity, oxidative stress and altered proteome in SK-N-SH cells.
Primchanien Moongkarndi,Chatchawan Srisawat,Putita Saetun,Jiraporn Jantaravinid,Chayanon Peerapittayamongkol,Rungtip Soi-ampornkul,Sarawut Junnu,Supachok Sinchaikul,Shui-Tein Chen,Patcharakajee Charoensilp,Visith Thongboonkerd,Neelobol Neungton +11 more
TL;DR: The significant protective effects of mangosteen extract against A beta-induced cytotoxicity, increased ROS, and increased caspase activity in SK-N-SH cells are reported.
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Association of SNP in exon 1 of HBS1L with hemoglobin F level in β0-thalassemia/hemoglobin E
Riyaz Ahmad Pandit,Saovaros Svasti,Orapan Sripichai,Thongperm Munkongdee,Kanokporn Triwitayakorn,Pranee Winichagoon,Suthat Fucharoen,Chayanon Peerapittayamongkol +7 more
TL;DR: QTL mapping provides for the first time evidence that C allele is associated with elevated Hb F level among β0-thalassemia/Hb E patients with XmnI-Gγ−/−and Xmni- Gγ+/−polymorphisms.
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Profiling the mitochondrial proteome of Leber's Hereditary Optic Neuropathy (LHON) in Thailand: down-regulation of bioenergetics and mitochondrial protein quality control pathways in fibroblasts with the 11778G>A mutation.
Aung Win Tun,Sakdithep Chaiyarit,Supannee Kaewsutthi,Wanphen Katanyoo,Wanicha Chuenkongkaew,Masayoshi Kuwano,Takeshi Tomonaga,Chayanon Peerapittayamongkol,Visith Thongboonkerd,Patcharee Lertrit +9 more
TL;DR: A proteomic approach to samples from affected and unaffected individuals from 3 pedigrees and from 5 unrelated controls revealed similar proteomic responses to 11778G>A mutation in both affected and affected individuals, and differentially expressed proteins revealed two broad groups.