C
Chee-Mun Fang
Researcher at University of Nottingham Malaysia Campus
Publications - 31
Citations - 1205
Chee-Mun Fang is an academic researcher from University of Nottingham Malaysia Campus. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 13, co-authored 26 publications receiving 813 citations. Previous affiliations of Chee-Mun Fang include Monash University Malaysia Campus & University of Malaya.
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Intracellular Targeting Mechanisms by Antimicrobial Peptides.
TL;DR: This review focuses on the major intracellular targeting activities reported in AMPs, which include nucleic acids and protein biosynthesis and protein-folding, protease, cell division, cell wall biosynthesis, and lipopolysaccharide inhibition.
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E-cadherin: Its dysregulation in carcinogenesis and clinical implications
TL;DR: The multifaceted effect E-cadherin expression has on cellular functions in the context of carcinogenesis as well as its clinical implications in diagnosis, prognosis and therapeutics are summarized.
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Critical role of IRF-5 in regulation of B-cell differentiation
TL;DR: The results reveal that the age-related splenomegaly in Irf5−/− mice is associated with an accumulation of CD19+B220− B cells with impaired functions and show the role of IRF-5 in the direct regulation of the plasma cell commitment factor Blimp-1 and in B-cell terminal differentiation.
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The TRAIL to cancer therapy: Hindrances and potential solutions.
Sonia How Ming Wong,Wei Yang Kong,Chee-Mun Fang,Hwei-San Loh,Lay Hong Chuah,Syahril Abdullah,Siew Ching Ngai +6 more
TL;DR: The apoptotic mechanisms via extrinsic and intrinsic apoptotic pathways, as well as the apoptotic resistance mechanisms are summarized and the current strategies in overcoming resistance to TRAIL-induced apoptosis in pre-clinical and clinical settings are discussed.
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Antibacterial, Anticancer and Neuroprotective Activities of Rare Actinobacteria from Mangrove Forest Soils
TL;DR: The results obtained in this study suggested that rare actinobacteria discovered from mangrove environment could be potential sources of antibacterial, anticancer and neuroprotective agents.