Chenli Qiu

TL;DR: In this paper, the authors dissect the kinetic emergence of different effector mechanisms across the spectrum of H7N9 disease and recovery and find that a diversity of response mechanisms contribute to resolution and survival.

TL;DR: It is revealed that LAG-3 on T cells delivers an inhibitory signal to downregulate T cell functionality, thereby playing an immunoregulatory role during persistent HIV-1 infection and providing an important target for enhancing immune reconstitution in HIV-infected patients.

TL;DR: Molecular and phenotypic analysis is used to establish persistence of clonally diverse CD8+ T cell populations during fatal infection and proposes that effective expansion of cross-reactive influenza-specific TCRαβ clonotypes with appropriate transcriptome signatures is needed for early protection against severe influenza disease.

TL;DR: In this article , a human antibody named 76E1 was isolated from a COVID-19 convalescent patient, and reported that it has broad-range neutralizing activity against multiple α- and β-coronaviruses, including the SARS-CoV-2 variants.

TL;DR: It is suggested that anti-IL-23 antibody is effective in protecting allograft rejection and the development of chronic OB in allo-tracheal transplantation and may have implications for new therapies to prevent OB and allografted rejection in human lung transplantation.