C
Choon-Gon Jang
Researcher at Sungkyunkwan University
Publications - 296
Citations - 6724
Choon-Gon Jang is an academic researcher from Sungkyunkwan University. The author has contributed to research in topics: Dopaminergic & Conditioned place preference. The author has an hindex of 38, co-authored 282 publications receiving 5573 citations. Previous affiliations of Choon-Gon Jang include University of Mississippi & University of Mississippi Medical Center.
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Journal ArticleDOI
Neuroprotective effects of chlorogenic acid on scopolamine-induced amnesia via anti-acetylcholinesterase and anti-oxidative activities in mice
Seung-Hwan Kwon,Ha-Kyung Lee,Ji-Ah Kim,Sa-Ik Hong,Hyoung-Chun Kim,Tae-Hyung Jo,Young-In Park,Chong-Kil Lee,Yong-Bin Kim,Seok-Yong Lee,Choon-Gon Jang +10 more
TL;DR: Results indicate that chlorogenic acid may exert anti-amnesic activity via inhibition of acetylcholinesterase and malondialdehyde in the hippocampus and frontal cortex in a dose-dependent manner.
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Prenatal and postnatal exposure to bisphenol a induces anxiolytic behaviors and cognitive deficits in mice
TL;DR: The results suggest that long‐term BPA exposure in mice can induce anxiolytic behaviors, cognitive deficits and changes in the dopaminergic and NMDAergic systems.
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Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model.
Seung Hyun Baek,So Jung Park,Jae In Jeong,Sung Hyun Kim,Jihoon Han,Jae Won Kyung,Sang-Ha Baik,Yuri Choi,Bo Youn Choi,Jin Su Park,Gahee Bahn,Ji Hyun Shin,Doo Sin Jo,Joo Yong Lee,Choon-Gon Jang,Thiruma V. Arumugam,Thiruma V. Arumugam,Jongpil Kim,Jeung Whan Han,Jae-Young Koh,Dong-Hyung Cho,Dong-Gyu Jo +21 more
TL;DR: The inhibition of Drp1 restored amyloid-β (Aβ)-mediated mitochondrial dysfunctions and synaptic depression in neurons and significantly reduced lipid peroxidation, BACE1 expression, and Aβ deposition in the brain of AD mice, suggesting that neuropathology and combined cognitive decline can be attributed to hyperactivation ofDrp1 in the pathogenesis of AD.
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Loganin improves learning and memory impairments induced by scopolamine in mice.
TL;DR: Loganin may have anti-amnesic activity that may hold significant therapeutic value in alleviating certain memory impairments observed in Alzheimer's disease.
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Loganin protects against hydrogen peroxide-induced apoptosis by inhibiting phosphorylation of JNK, p38, and ERK 1/2 MAPKs in SH-SY5Y cells.
Seung-Hwan Kwon,Ji-Ah Kim,Sa-Ik Hong,Yang-Hee Jung,Hyoung-Chun Kim,Seok-Yong Lee,Choon-Gon Jang +6 more
TL;DR: Loganin's neuroprotective properties indicate that this compound may be a potential therapeutic agent for the treatment of neurodegenerative diseases.