J
Jongpil Kim
Researcher at Dongguk University
Publications - 38
Citations - 795
Jongpil Kim is an academic researcher from Dongguk University. The author has contributed to research in topics: Reprogramming & Induced pluripotent stem cell. The author has an hindex of 13, co-authored 38 publications receiving 563 citations.
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Journal ArticleDOI
Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model.
Seung Hyun Baek,So Jung Park,Jae In Jeong,Sung Hyun Kim,Jihoon Han,Jae Won Kyung,Sang-Ha Baik,Yuri Choi,Bo Youn Choi,Jin Su Park,Gahee Bahn,Ji Hyun Shin,Doo Sin Jo,Joo Yong Lee,Choon-Gon Jang,Thiruma V. Arumugam,Thiruma V. Arumugam,Jongpil Kim,Jeung Whan Han,Jae-Young Koh,Dong-Hyung Cho,Dong-Gyu Jo +21 more
TL;DR: The inhibition of Drp1 restored amyloid-β (Aβ)-mediated mitochondrial dysfunctions and synaptic depression in neurons and significantly reduced lipid peroxidation, BACE1 expression, and Aβ deposition in the brain of AD mice, suggesting that neuropathology and combined cognitive decline can be attributed to hyperactivation ofDrp1 in the pathogenesis of AD.
Journal ArticleDOI
Electromagnetized gold nanoparticles mediate direct lineage reprogramming into induced dopamine neurons in vivo for Parkinson's disease therapy
Junsang Yoo,Euiyeon Lee,Hee Young Kim,Dong-ho Youn,Junghyun Jung,Hongwon Kim,Yujung Chang,Wonwoong Lee,Jaein Shin,Soonbong Baek,Wonhee Jang,Won Jun,Soochan Kim,Jongki Hong,Hi-Joon Park,Christopher J. Lengner,Sang Hyun Moh,Youngeun Kwon,Jongpil Kim +18 more
TL;DR: This study shows that electromagnetized gold nanoparticles (AuNPs) in the presence of specific EMF conditions facilitate an efficient direct lineage reprogramming to induced dopamine neurons in vitro and in vivo.
Journal ArticleDOI
Efficient mRNA delivery with graphene oxide-polyethylenimine for generation of footprint-free human induced pluripotent stem cells.
Hye Yeon Choi,Tae-Jin Lee,Gwang-Mo Yang,Jaesur Oh,Jihye Won,Jihae Han,Gun-Jae Jeong,Jongpil Kim,Jin-Hoi Kim,Byung-Soo Kim,Ssang-Goo Cho +10 more
TL;DR: It is demonstrated that mRNA delivery using GO-PEI-RNA complexes can efficiently generate "footprint-free" iPSCs, which may advance the translation of iPSC technology into the clinical settings.
Journal ArticleDOI
Cell reprogramming into the pluripotent state using graphene based substrates.
TL;DR: It is found that the graphene substrate significantly improved cellular reprogramming efficiency by inducing mesenchymal-to-epithelial-transition (MET) which is known to affect H3K4me3 levels.
Journal ArticleDOI
Two extension block Kirschner wire technique for mallet finger fractures
TL;DR: The Kirschner-wire technique, when properly applied, produces satisfactory results both clinically and radiologically, and is believed to be a viable technique for displaced mallet finger fractures.