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Christer Köhler

Researcher at Astra

Publications -  112
Citations -  9176

Christer Köhler is an academic researcher from Astra. The author has contributed to research in topics: Hippocampal formation & Subiculum. The author has an hindex of 53, co-authored 112 publications receiving 9070 citations. Previous affiliations of Christer Köhler include Karolinska Institutet & AstraZeneca.

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Specific in vitro and in vivo binding of 3H-raclopride a potent substituted benzamide drug with high affinity for dopamine D-2 receptors in the rat brain

TL;DR: The results suggest that 3H-raclopride labels dopamine D-2 receptors with high specificity in the rat brain both in vitro and in vivo, and thus, that it should be a useful tool in studies of central dopamine D -2 receptors.
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II: Excitotoxic models for neurodegenerative disorders

TL;DR: Although a biochemical link between endogenousexcitotoxins and human neurodegenerative disorders remains elusive at present, pharmacological blockade of excitotoxicity may constitute a novel therapeutic strategy for the treatment of these disease states.
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Septal neurons containing glutamic acid decarboxylase immunoreactivity project to the hippocampal region in the rat brain.

TL;DR: Findings provide evidence that a significant portion of the septohippocampal projection may utilize gamma-aminobutyric acid as a neurotransmitter.
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Identification of serotonin and non-serotonin-containing neurons of the mid-brain raphe projecting to the entorhinal area and the hippocampal formation. A combined immunohistochemical and fluorescent retrograde tracing study in the rat brain.

TL;DR: The findings indicate that both serotonin- and non-serotonin-containing neurons in the raphe innervate the hippocampal region, that these projections may be crossed but not bilateral, and that the same neuron in theRaphe may influence the neural activity in the entorhinal area and the hippocampus simultaneously.
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Intrinsic projections of the retrohippocampal region in the rat brain. I. The subicular complex

TL;DR: The intrahippocampal projections of the subicular complex were studied in the rat with the aid of the anterogradely transported lectin Phaseolus vulgaris leucoagglutinin (PHA‐L) and axons and terminal processes immunoreactive for PHA‐ L were traced to their respective terminal fields within the hippocampal region.