C
Christiaan N. Levelt
Researcher at VU University Amsterdam
Publications - 55
Citations - 3448
Christiaan N. Levelt is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Visual cortex & Monocular deprivation. The author has an hindex of 27, co-authored 52 publications receiving 3098 citations. Previous affiliations of Christiaan N. Levelt include Netherlands Institute for Neuroscience & Royal Netherlands Academy of Arts and Sciences.
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A genetically encoded calcium indicator for chronic in vivo two-photon imaging
Marco Mank,Alexandre Ferrão Santos,Stephan Direnberger,Thomas D. Mrsic-Flogel,Sonja B. Hofer,Valentin Stein,Thomas Hendel,Dierk F. Reiff,Christiaan N. Levelt,Alexander Borst,Tobias Bonhoeffer,Mark Hübener,Oliver Griesbeck +12 more
TL;DR: The genetically encoded calcium indicator TN-XXL allows repeated imaging of response properties from individual, identified neurons in vivo, which will be crucial for gaining new insights into cellular mechanisms of plasticity, regeneration and disease.
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Critical-Period Plasticity in the Visual Cortex
TL;DR: It is shown that plasticity in the visual cortex is present well before, and long after, the peak of the critical period and described the established mechanisms and point out where more experimental work is needed.
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Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure.
Serge A. van de Pavert,Albena Kantardzhieva,Anna Malysheva,Jan Meuleman,Inge Versteeg,Christiaan N. Levelt,Jan Klooster,Sylvia Geiger,Mathias W. Seeliger,P. Rashbass,André Le Bivic,Jan Wijnholds +11 more
TL;DR: It is proposed that during light exposure Crb1 is essential to maintain, but not assemble, adherens junctions between photoreceptors and Müller glia cells and prevents retinal disorganization and dystrophy.
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Elimination of Inhibitory Synapses Is a Major Component of Adult Ocular Dominance Plasticity
Daniëlle van Versendaal,Rajeev Rajendran,M. Hadi Saiepour,Jan Klooster,Laura A. Smit-Rigter,Jean-Pierre Sommeijer,Chris I. De Zeeuw,Chris I. De Zeeuw,Sonja B. Hofer,J. Alexander Heimel,Christiaan N. Levelt +10 more
TL;DR: It is proposed that in the adult visual cortex the experience-induced loss of inhibition may effectively strengthen specific visual inputs with limited need for rearranging the excitatory circuitry.
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Restoration of early thymocyte differentiation in T-cell receptor beta-chain-deficient mutant mice by transmembrane signaling through CD3 epsilon.
TL;DR: It is shown that the CD4+8+ double-positive (DP) stage can be induced by treatment of fetal thymic organ cultures with anti-CD3 epsilon monoclonal antibodies in several TCR beta-chain-deficient mouse strains: severe combined immunodeficient mice, mice carrying a mutation in the recombination activating gene 1 (Rag-1), or micecarrying a deletion in the TCRbeta-chain locus itself.