Mathias W. Seeliger

TL;DR: It is shown that expression of archaebacterial halorhodopsin in light-insensitive cones can substitute for the native phototransduction cascade and restore light sensitivity in mouse models of retinitis pigmentosa.

TL;DR: It is shown in the adult mouse retina that acute hypoxia dose-dependently stimulates expression of Epo, fibroblast growth factor 2 and vascular endothelial growth factor via Hypoxia-inducible factor-1α (HIF-1 α) stabilization.

TL;DR: The data show that different mutations in CDH23 result in USH1D with a variable retinal phenotype, and it is shown that mutations in the mouse ortholog cause disorganization of inner ear stereocilia and deafness in the waltzer mouse.

TL;DR: The mutations uncovered by behavioral assays of 450 zebrafish mutants provide distinct entry points for the study of visual pathways and set the stage for a genetic dissection of vertebrate vision.

TL;DR: Department of Ophthalmology, Stanford University School of Medicine, Stanford, California, USA; andDepartment of Psychology, Columbia University, New York, NewYork, USA, for the International Society for Clinical Electrophysiology of Vision.