C
Christian Dietz
Researcher at University of Konstanz
Publications - 18
Citations - 402
Christian Dietz is an academic researcher from University of Konstanz. The author has contributed to research in topics: Species complex & Western Palaearctic. The author has an hindex of 9, co-authored 18 publications receiving 278 citations.
Papers
More filters
Journal ArticleDOI
KNIME for reproducible cross-domain analysis of life science data
Alexander Fillbrunn,Christian Dietz,Julianus Pfeuffer,René Rahn,Gregory A. Landrum,Michael R. Berthold +5 more
TL;DR: This review paper presents selected extensions from the life sciences that simplify data exploration, analysis, and visualization and are interoperable due to KNIME's unified data model.
Book ChapterDOI
KNIME for Open-Source Bioimage Analysis: A Tutorial.
TL;DR: The KNIME Image Processing Extension is introduced, which adds the capabilities to process and analyse huge amounts of images, and opens up new possibilities for inter-domain analysis of image data in an understandable and reproducible way.
Journal ArticleDOI
90K, an interferon-stimulated gene product, reduces the infectivity of HIV-1
Veronika Lodermeyer,Kristina Suhr,Nicola Schrott,Christian Kolbe,Christina M. Stürzel,Daniela Krnavek,Jan Münch,Christian Dietz,Tanja Waldmann,Frank Kirchhoff,Christine Goffinet +10 more
TL;DR: 90K constitutes a novel antiviral factor that reduces the particle infectivity of HIV-1, involving interference with the maturation and incorporation of HIV -1 Env molecules into virions.
Journal ArticleDOI
Development of a neural rosette formation assay (RoFA) to identify neurodevelopmental toxicants and to characterize their transcriptome disturbances
Nadine Dreser,Katrin Madjar,Anna-Katharina Holzer,Marion Kapitza,Christopher Scholz,Petra Kranaster,Simon Gutbier,Simon Gutbier,Stefanie Klima,David Kolb,Christian Dietz,Timo Trefzer,Timo Trefzer,Johannes Meisig,Christoph van Thriel,Margit Henry,Michael R. Berthold,Nils Blüthgen,Agapios Sachinidis,Jörg Rahnenführer,Jan G. Hengstler,Tanja Waldmann,Marcel Leist +22 more
TL;DR: A new version of the human stem cell-based test STOP-tox (UKN) was developed, and a prediction model for the RoFA was developed to identify gene dysregulations that are particularly predictive for disturbed rosette formation.
Journal ArticleDOI
Grouping of histone deacetylase inhibitors and other toxicants disturbing neural crest migration by transcriptional profiling
Nadine Dreser,Bastian Zimmer,Christian Dietz,Elena Sügis,Giorgia Pallocca,Johanna Nyffeler,Johannes Meisig,Nils Blüthgen,Nils Blüthgen,Michael R. Berthold,Tanja Waldmann,Marcel Leist +11 more
TL;DR: The data suggest that a given functional effect can be associated with highly diverse signatures of transcript changes and statistically significant grouping of mechanistically-related compounds can be achieved on the basis of few genes with small regulations, and incorporation of mechanistic markers in functional in vitro tests may support read-across procedures.