C
Christian Junghanss
Researcher at University of Rostock
Publications - 175
Citations - 3011
Christian Junghanss is an academic researcher from University of Rostock. The author has contributed to research in topics: Transplantation & Medicine. The author has an hindex of 20, co-authored 144 publications receiving 2514 citations.
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Uncoupling protein 2 deficiency of non-cancerous tissues inhibits the progression of pancreatic cancer in mice.
Denis Revskij,Jakob Runst,Camilla Umstätter,Luise Ehlers,Sarah Rohde,Dietmar Zechner,Manuela Bastian,Brigitte Müller-Hilke,Georg Fuellen,Larissa Henze,H. Murua Escobar,Christian Junghanss,Axel Kowald,Uwe Walter,Rüdiger Köhling,Olaf Wolkenhauer,Robert Jaster +16 more
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Polymorphism nt7778G/T In Mitochondrial ATP8 Gene Promotes Protective Effect On Reactive Oxygen Species Level In Murine Hematopoietic Cells During Aging
Christin Kretzschmar,Catrin Roolf,Katrin Timmer,Gudrun Knübel,Anett Sekora,Sarah Müller,Markus Tiedge,Simone Baltrusch,Rüdiger Köhling,Saleh M. Ibrahim,Mathias Freund,Christian Junghanss +11 more
TL;DR: Compared two conplastic mouse strains differing in one point mutation in the mtDNA affecting the respiratory chain, bone marrow cell composition of both strains showed an increase of hematopoietic stem cells (LSK cells: lineage-, sca-1+, c-kit+) and a significant increase in ATP levels during experimental time span from 3 to 24 months.
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Small but effective: trophoblast-derived miRNAs transported via exosomes as guardians against viral infections
TL;DR: Findings indicate a pivotal role of C19MC miRNAs in pregnancy by counteracting embryonal and fetal infections and, simultaneously, raise several further questions, including therapeutic approaches.
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Engraftment Effects of Intra Bone Marrow Compared to Intravenous Transplantation of Allogeneic Hematopoietic Stem Cells Following a Reduced Intensity Conditioning in a DLA-Identical Canine Littermate Model
Juliane Werner,Stephanie Schaefer,Sandra Lange,Christoph Machka,Gudrun Knuebel,Anett Sekora,Catrin Roolf,Hugo Murua Escobar,Heike Vogel,Iris Lindner,Mathias Freund,Christian Junghanss +11 more
TL;DR: Examining the feasibility and efficiency of IBM allogeneic HSCT in comparison to IV HS CT in dog leukocyte antigen (DLA) identical canine littermates using a RIC regimen and results demonstrated faster engraftment with an IBM HSCT approach compared to intravenous (IV) HSCT following myeloablative conditioning found it feasible.
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Evaluation of the Synergistic Potential of Simultaneous Pan- or Isoform-Specific BET and SYK Inhibition in B-Cell Lymphoma: An In Vitro Approach
Sina Sender,Ahmad Wael Sultan,Daniel Palmer,Dirk Koczan,Anett Sekora,J. Thaddeus Beck,Ekkehard Schuetz,Leila Taher,Bertram Brenig,Georg Fuellen,Christian Junghanss,H. Murua Escobar +11 more
TL;DR: The simultaneous inhibition of SYK and BET showed enhanced anti-proliferative effects, as well as inducing a distinct combination-specific gene expression profile, suggesting SYk and BET inhibition as a promising combination in the treatment of B-cell lymphoma.