C
Christine Bowman
Researcher at Royal Hallamshire Hospital
Publications - 14
Citations - 1626
Christine Bowman is an academic researcher from Royal Hallamshire Hospital. The author has contributed to research in topics: Herpes simplex virus & Men who have sex with men. The author has an hindex of 8, co-authored 14 publications receiving 1339 citations.
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Journal ArticleDOI
Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial.
Sheena McCormack,David Dunn,Monica Desai,David Dolling,Mitzy Gafos,Richard Gilson,Richard Gilson,Ann Sullivan,Amanda Clarke,Iain Reeves,Gabriel Schembri,Nicola Mackie,Christine Bowman,Charles J.N. Lacey,Vanessa Apea,Michael Brady,Julie Fox,Stephen Taylor,Simone Antonucci,Saye Khoo,James F. Rooney,Anthony Nardone,Martin Fisher,Alan McOwan,Andrew N. Phillips,Anne M Johnson,Brian Gazzard,ON Gill +27 more
TL;DR: In this high incidence population, daily tenofovir–emtricitabine conferred even higher protection against HIV than in placebo-controlled trials, refuting concerns that effectiveness would be less in a real-world setting.
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An analysis of baseline data from the PROUD study: an open-label randomised trial of pre-exposure prophylaxis
David Dolling,Monica Desai,Alan McOwan,Richard Gilson,Amanda Clarke,Martin Fisher,Gabriel Schembri,Ann Sullivan,Nicola Mackie,Iain Reeves,Mags Portman,John Saunders,Julie Fox,Jake Bayley,Michael Brady,Christine Bowman,Charles J.N. Lacey,Stephen M. Taylor,David White,Simone Antonucci,Mitzy Gafos,Sheena McCormack,ON Gill,David Dunn,Anthony Nardone +24 more
TL;DR: The PROUD study population are at substantially higher risk of acquiring HIV infection sexually than the overall population of GMSM attending sexual health clinics in England, and demonstrate that, despite broad eligibility criteria, the population interested in PrEP was highly selective.
Journal ArticleDOI
The contribution of the HIV specialist nurse to HIV care: a scoping review
TL;DR: A review of the literature details current understanding of the role of HIV specialist nurses and the contribution that they make to HIV care, with limited evidence to indicate clinical effectiveness.
Journal ArticleDOI
Asymptomatic herpes simplex virus shedding from the genital tract whilst on suppressive doses of oral acyclovir.
TL;DR: Failure to suppress asymptomatic shedding during prophylactic acyclovir therapy may have implications for sexual transmission to partners and vertical transmission to neonates and requires further study.
Journal ArticleDOI
Safety, immunogenicity and efficacy assessment of HIV immunotherapy in a multi-centre, double-blind, randomised, Placebo-controlled Phase Ib human trial.
Marta Boffito,Julie Fox,Christine Bowman,Martin Fisher,Chloe Orkin,Edmund Wilkins,Akil Jackson,Olga Pleguezuelos,Stuart Robinson,Gregory Alan Stoloff,Wilson Caparros-Wanderley +10 more
TL;DR: HIV-v is safe and can elicit T- and B-cell responses in ART-naive HIV patients that significantly reduce viral load, and appears to have potential as an immunotherapeutic anti-viral agent.