S
Stephen Taylor
Researcher at Heart of England NHS Foundation Trust
Publications - 20
Citations - 2650
Stephen Taylor is an academic researcher from Heart of England NHS Foundation Trust. The author has contributed to research in topics: Viral load & Population. The author has an hindex of 17, co-authored 20 publications receiving 2349 citations. Previous affiliations of Stephen Taylor include University of Birmingham.
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Journal ArticleDOI
Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial.
Sheena McCormack,David Dunn,Monica Desai,David Dolling,Mitzy Gafos,Richard Gilson,Richard Gilson,Ann Sullivan,Amanda Clarke,Iain Reeves,Gabriel Schembri,Nicola Mackie,Christine Bowman,Charles J.N. Lacey,Vanessa Apea,Michael Brady,Julie Fox,Stephen Taylor,Simone Antonucci,Saye Khoo,James F. Rooney,Anthony Nardone,Martin Fisher,Alan McOwan,Andrew N. Phillips,Anne M Johnson,Brian Gazzard,ON Gill +27 more
TL;DR: In this high incidence population, daily tenofovir–emtricitabine conferred even higher protection against HIV than in placebo-controlled trials, refuting concerns that effectiveness would be less in a real-world setting.
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Long-term persistence of primary genotypic resistance after HIV-1 seroconversion.
David Pao,Ushan Andrady,Janette Clarke,Gillian Dean,Susan M. Drake,Martin Fisher,Tanya Green,Siva Kumar,Maurice Murphy,A Tang,Stephen Taylor,David White,Gillian Underhill,Deenan Pillay,Patricia A. Cane +14 more
TL;DR: Data support the recommendation that all new HIV diagnoses in areas where primary resistance may occur should undergo genotyping irrespective of whether the date of seroconversion is known, and certain resistance-associated mutations are highly stable.
Journal ArticleDOI
Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the male and female genital tract.
TL;DR: In the female genital tract, the nucleoside analogues exhibit high accumulation ratios, whereas protease inhibitors have limited penetration; however, substantial variability exists between individuals and study centres.
Journal ArticleDOI
Incidence and impact of resistance against approved antiretroviral drugs
TL;DR: The biological basis of antiretroviral drug resistance, and the prevalence of specific drug resistance associated mutations in patients treated with the three currently available classes of agents, are addressed.
Journal ArticleDOI
The effects of antiretroviral therapy on HIV-1 RNA loads in seminal plasma in HIV-positive patients with and without urethritis.
S T Sadiq,Stephen Taylor,Steve Kaye,J Bennett,R Johnstone,P Byrne,Andrew Copas,Susan M. Drake,Deenan Pillay,Ian Weller +9 more
TL;DR: Effective antiretroviral therapy appeared to limit the effect of urethritis on SVL, increasing the potential risk of transmitting both wild type and drug resistant strains of HIV-1.