C
Christine E. Campbell
Researcher at University at Buffalo
Publications - 43
Citations - 2444
Christine E. Campbell is an academic researcher from University at Buffalo. The author has contributed to research in topics: Gene & Wilms' tumor. The author has an hindex of 23, co-authored 42 publications receiving 2338 citations. Previous affiliations of Christine E. Campbell include University of Toronto & Cleveland Clinic.
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Journal ArticleDOI
Disruption of the murine nuclear factor I-A gene (Nfia) results in perinatal lethality, hydrocephalus, and agenesis of the corpus callosum
Liomar das Neves,Cynthia S. Duchala,Fatima Godinho,Musa A. Haxhiu,Clemencia Colmenares,Wendy B. Macklin,Christine E. Campbell,Kenneth G. Butz,Richard M. Gronostajski +8 more
TL;DR: It is shown that disruption of the Nfia gene causes perinatal lethality, with >95% of homozygous N fia(-/-) animals dying within 2 weeks after birth.
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Human TBX1 Missense Mutations Cause Gain of Function Resulting in the Same Phenotype as 22q11.2 Deletions
TL;DR: It is concluded that TBX1 gain-of-function mutations can result in the same phenotypic spectrum as haploinsufficiency caused by loss of function mutations or deletions.
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Synergistic Transcriptional Activation of the Tissue Inhibitor of Metalloproteinases-1 Promoter via Functional Interaction of AP-1 and Ets-1 Transcription Factors
TL;DR: The results suggest that AP-1 tethers c-Ets-1 to the TIMP-1 promoter via protein-protein interaction to achieve Ets-dependent transcriptional regulation.
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Nfix Regulates Fetal-Specific Transcription in Developing Skeletal Muscle
Graziella Messina,Stefano Biressi,Stefania Monteverde,Alessandro Magli,Marco Cassano,Laura Perani,Elena Roncaglia,Enrico Tagliafico,Linda M. Starnes,Christine E. Campbell,Milena Grossi,David J. Goldhamer,Richard M. Gronostajski,Giulio Cossu +13 more
TL;DR: Premature expression of Nfix activates fetal and suppresses embryonic genes in embryonic muscle, whereas muscle-specific ablation of N fix prevents fetal and maintains embryonic gene expression in the fetus, therefore, Nfix acts as a transcriptional switch from embryonic to fetal myogenesis.
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The spectrum of mutations in TBX3: Genotype/Phenotype relationship in ulnar-mammary syndrome.
Michael J. Bamshad,Michael J. Bamshad,Trung Le,W. S. Watkins,Missy Dixon,Bridget E. Kramer,Amy D. Roeder,John C. Carey,S. Root,Albert Schinzel,L. Van Maldergem,R.J.M. Gardner,R. C. Lin,Christine E. Seidman,Jonathan G. Seidman,R. Wallerstein,Ellen Moran,R. Sutphen,Christine E. Campbell,Lynn B. Jorde +19 more
TL;DR: It is suggested that a domain(s) outside the T-box is highly conserved and important for the function of TBX3, and no obvious phenotypic differences between those who have missense mutations and those who has deletions or frameshifts are found.