Christine Flaxman

TL;DR: It is demonstrated that an apparent mis-match between crime-stain and a suspect DNA profile does not necessarily result in an exclusion, and the duplication guideline is robust by applying a statistical theory that models three key parameters - namely the incidence of allele drop-out, laboratory contamination and stutter.

TL;DR: In this paper , the authors explored multiple human virus species in the Diabetes Virus Detection (DiViD) study cases using innovative methods, including virus passage in cell cultures, including gene amplification and detection of virus-coded proteins by immunofluorescence.

TL;DR: In this article , the misexpression of microRNAs in an iPSC-based disease model of FUS ALS was explored and the downregulation of miR-139, an MN-enriched microRNA, in FUS and sporadic ALS MN was identified.

TL;DR: In this article , the authors identified 14 non-coding de novo variants affecting a 42-bp conserved region encompassed by a regulatory element in intron 2 of the hexokinase 1 gene (HK1).

TL;DR: The trends observed in C-peptide decline and β-cell loss in pancreas donors from the nPOD biobank and the Exeter Archival Diabetes Biobank are explored, confirming that β-cells can remain following type 1 diabetes onset.