C
Christine Poitou
Researcher at University of Paris
Publications - 199
Citations - 13688
Christine Poitou is an academic researcher from University of Paris. The author has contributed to research in topics: Adipose tissue & Weight loss. The author has an hindex of 54, co-authored 171 publications receiving 11434 citations. Previous affiliations of Christine Poitou include Paris Descartes University & French Institute of Health and Medical Research.
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Journal ArticleDOI
Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss.
Raffaella Cancello,Corneliu Henegar,Nathalie Viguerie,Soraya Taleb,Christine Poitou,Christine Rouault,Muriel Coupaye,Véronique Pelloux,Danielle Hugol,Jean Luc Bouillot,Anne Bouloumié,Giorgio Barbatelli,Saverio Cinti,Per-Arne Svensson,Gregory S. Barsh,Jean-Daniel Zucker,Arnaud Basdevant,Dominique Langin,Karine Clément +18 more
TL;DR: It is shown that improvement of the inflammatory profile after weight loss is related to a reduced number of macrophages in scWAT, and MCP-1, PLAUR, CSF-3, and HIF-1alpha may play roles in the attraction of macophages inscWAT.
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Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: links with metabolic and low-grade inflammation markers.
Jean-Pierre Furet,Ling-Chun Kong,Julien Tap,Christine Poitou,Arnaud Basdevant,Jean-Luc Bouillot,Denis Mariat,Gérard Corthier,Joël Doré,Corneliu Henegar,Salwa W. Rizkalla,Karine Clément +11 more
TL;DR: Results suggest that components of the dominant gut microbiota rapidly adapt in a starvation-like situation induced by RYGB while the F. prausnitzii species is directly linked to the reduction in low-grade inflammation state in obesity and diabetes independently of calorie intake.
Journal ArticleDOI
Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects
Karine Clément,Nathalie Viguerie,Nathalie Viguerie,Christine Poitou,Claire Carette,Véronique Pelloux,Cyrile Anne Curat,Audrey Sicard,Audrey Sicard,Sophie Rome,Arriel Benis,Arriel Benis,Jean-Daniel Zucker,Jean-Daniel Zucker,Hubert Vidal,Martine Laville,Gregory S. Barsh,Arnaud Basdevant,Vladimir Stich,Vladimir Stich,Raffaella Cancello,Dominique Langin,Dominique Langin +22 more
TL;DR: Weight loss improves the inflammatory profile of obese subjects through a decrease of proinflammatory factors and an increase of anti‐inflammatory molecules and the beneficial effect of weight loss on obesity‐related complications may be associated with the modification of theinflammatory profile in adipose tissue.
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Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients
Pierre Bedossa,Christine Poitou,Christine Poitou,Nicolas Veyrie,Jean-Luc Bouillot,Arnaud Basdevant,Arnaud Basdevant,Valérie Paradis,Joan Tordjman,Joan Tordjman,Karine Clément,Karine Clément +11 more
TL;DR: The aim was to build an algorithm along with a scoring system for histopathologic classification of liver lesions that covers the entire spectrum of lesions in morbidly obese patients, and suggest describing liver lesions using the SAF score.
Journal ArticleDOI
Increased Infiltration of Macrophages in Omental Adipose Tissue Is Associated With Marked Hepatic Lesions in Morbid Human Obesity
Raffaella Cancello,Joan Tordjman,Christine Poitou,Gaël Guilhem,Jean Luc Bouillot,Danielle Hugol,Christiane Coussieu,Arnaud Basdevant,Avner Bar Hen,Pierre Bedossa,Michèle Guerre-Millo,Karine Clément +11 more
TL;DR: The data suggest that the presence of macrophages in omental WAT participates in the cellular mechanisms favoring hepatic fibroinflammatory lesions in obese patients, and the best predictive model for the severity of hepatic damage includes adiponectinemia, AST, and o mental WATmacrophages.