C
Christof Taxis
Researcher at University of Marburg
Publications - 36
Citations - 3061
Christof Taxis is an academic researcher from University of Marburg. The author has contributed to research in topics: Degron & Protein degradation. The author has an hindex of 15, co-authored 33 publications receiving 2675 citations. Previous affiliations of Christof Taxis include European Bioinformatics Institute.
Papers
More filters
Journal ArticleDOI
A versatile toolbox for PCR-based tagging of yeast genes: new fluorescent proteins, more markers and promoter substitution cassettes.
Carsten Janke,Maria M. Magiera,Nicole Rathfelder,Christof Taxis,Simone Reber,Hiromi Maekawa,Alexandra C. Moreno-Borchart,Georg Doenges,Etienne Schwob,Elmar Schiebel,Michael Knop,Michael Knop +11 more
TL;DR: Using the provided cassettes for N‐ and C‐terminal gene tagging or for deletion of any given gene, a set of only four primers is required, which makes this method very cost‐effective and reproducible.
Journal ArticleDOI
A LOV2 Domain-Based Optogenetic Tool to Control Protein Degradation and Cellular Function
TL;DR: This engineered degron module transfers the principle of light-regulated degradation to nonplant organisms and will be highly beneficial to control protein levels in biotechnological or biomedical applications and offers the potential to render a plethora of biological processes light-switchable.
Journal ArticleDOI
System of centromeric, episomal, and integrative vectors based on drug resistance markers for Saccharomyces cerevisiae.
Christof Taxis,Michael Knop +1 more
TL;DR: A system of shuttle vectors based on the widely used plasmids of the pRS series, using genes conferring resistance to Geneticin, nourseothricin, and hygromycin B as markers to enhance the flexibility of genetic manipulations and gene expression in yeast.
Journal ArticleDOI
Efficient protein depletion by genetically controlled deprotection of a dormant N‐degron
TL;DR: A dormant N‐degron that can be attached to the N‐terminus of a protein of interest that becomes deprotected upon expression of a site‐specific protease, which allows the control of protein abundance by a genetically encoded regulatory system.
Journal ArticleDOI
Spore number control and breeding in Saccharomyces cerevisiae: a key role for a self-organizing system.
Christof Taxis,Philipp J. Keller,Zaharoula Kavagiou,Lars Juhl Jensen,Julien Colombelli,Peer Bork,Ernst H. K. Stelzer,Michael Knop +7 more
TL;DR: It is shown that precise spore number control (SNC) fulfills two functions: maximizes the production of spores that are formed by a single cell and enhances intratetrad mating, whereby maximal amounts of germinated spores are able to return to a diploid lifestyle without intermediary mitotic division.