C
Christoph Sinning
Researcher at University of Hamburg
Publications - 139
Citations - 3903
Christoph Sinning is an academic researcher from University of Hamburg. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 21, co-authored 109 publications receiving 3222 citations. Previous affiliations of Christoph Sinning include University of Mainz.
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Journal ArticleDOI
Sensitive Troponin I Assay in Early Diagnosis of Acute Myocardial Infarction
Till Keller,Tanja Zeller,Dirk Peetz,Stergios Tzikas,Alexander Röth,Ewa Czyz,Christoph Bickel,Stephan Baldus,Ascan Warnholtz,Meike Fröhlich,Christoph Sinning,Medea S. Eleftheriadis,Philipp S. Wild,Renate B. Schnabel,Edith Lubos,Nicole Jachmann,Sabine Genth-Zotz,Felix Post,Viviane Nicaud,Laurence Tiret,Karl J. Lackner,Thomas Münzel,Stefan Blankenberg +22 more
TL;DR: The use of a sensitive assay for troponin I improves early diagnosis of acute myocardial infarction and risk stratification, regardless of the time of chest-pain onset.
Journal ArticleDOI
Serial changes in highly sensitive troponin I assay and early diagnosis of myocardial infarction.
Till Keller,Tanja Zeller,Francisco Ojeda,Stergios Tzikas,Lars Lillpopp,Christoph Sinning,Philipp S. Wild,Sabine Genth-Zotz,Ascan Warnholtz,Evangelos Giannitsis,Martin Möckel,Christoph Bickel,Dirk Peetz,Karl J. Lackner,Stephan Baldus,Thomas Münzel,Stefan Blankenberg +16 more
TL;DR: Among patients with suspected acute coronary syndrome, the introduction of highly sensitive troponin assays into clinical practice has substantially improved the evaluation of patients with chest pain and a serial change in hsTNI or cTnI levels from admission to 3 hours after admission may facilitate an early diagnosis of AMI.
Journal ArticleDOI
Diagnosis of Myocardial Infarction Using a High-Sensitivity Troponin I 1-Hour Algorithm
Johannes T Neumann,Nils A Sörensen,Tjark Schwemer,Francisco Ojeda,Rafael Bourry,Vanessa Sciacca,Sarina Schaefer,Christoph Waldeyer,Christoph Sinning,Thomas Renné,Thomas Renné,Martin Than,William A. Parsonage,Karin Wildi,Nataliya Makarova,Renate B. Schnabel,Ulf Landmesser,Christian Mueller,Louise Cullen,Jaimi H. Greenslade,Tanja Zeller,Stefan Blankenberg,M. Karakas,Dirk Westermann +23 more
TL;DR: Patients with possible AMI can be triaged within 1 hour after admission with no loss of safety compared with a 3-hour approach, when a low and sensitive cutoff is applied.
Journal ArticleDOI
Noninvasive Vascular Function Measurement in the Community Cross-Sectional Relations and Comparison of Methods
Renate B. Schnabel,Andreas Schulz,Philipp S. Wild,Christoph Sinning,Sandra Wilde,Medea S. Eleftheriadis,Stephanie Herkenhoff,Tanja Zeller,Edith Lubos,Karl J. Lackner,Ascan Warnholtz,Tommaso Gori,Stefan Blankenberg,Thomas Münzel +13 more
TL;DR: Noninvasive measures of conduit artery and peripheral arterial function are modestly correlated, differ in their relation to classical cardiovascular risk factors, and may thus reflect different pathologies.
Journal ArticleDOI
A Genome-Wide Association Study Identifies LIPA as a Susceptibility Gene for Coronary Artery Disease
Philipp S. Wild,Tanja Zeller,Arne Schillert,Silke Szymczak,Christoph Sinning,Arne Deiseroth,Renate B. Schnabel,Edith Lubos,Till Keller,Medea S. Eleftheriadis,Christoph Bickel,Hans J. Rupprecht,Sandra Wilde,Heidi Rossmann,Patrick Diemert,L. Adrienne Cupples,Claire Perret,Jeanette Erdmann,Klaus Stark,Marcus E. Kleber,Stephen E. Epstein,Benjamin F. Voight,Kari Kuulasmaa,Mingyao Li,Arne Schäfer,Norman Klopp,Peter S. Braund,Hendrik B. Sager,Serkalem Demissie,Carole Proust,Inke R. König,Heinz Erich Wichmann,Wibke Reinhard,Michael M. Hoffmann,Jarmo Virtamo,Mary Susan Burnett,David S. Siscovick,Per-Gunnar Wiklund,Liming Qu,Nour Eddine El Mokthari,John R. Thompson,Annette Peters,Albert V. Smith,Emmanuelle Yon,Jens Baumert,Christian Hengstenberg,Winfried März,Philippe Amouyel,Joseph M. Devaney,Stephen M. Schwartz,Olli Saarela,Nehal N. Mehta,Diana Rubin,Kaisa Silander,Alistair S. Hall,Jean Ferrières,Tamara B. Harris,Olle Melander,Frank Kee,Hakon Hakonarson,Juergen Schrezenmeir,Vilmundur Gudnason,Roberto Elosua,Dominique Arveiler,Alun Evans,Daniel J. Rader,Thomas Illig,Stefan Schreiber,Joshua C. Bis,David Altshuler,Maryam Kavousi,Jaqueline C M Witteman,André G. Uitterlinden,Albert Hofman,Aaron R. Folsom,Maja Barbalić,Eric Boerwinkle,Sekar Kathiresan,Muredach P. Reilly,Christopher J. O'Donnell,Nilesh J. Samani,Heribert Schunkert,François Cambien,Karl J. Lackner,Laurence Tiret,Veikko Salomaa,Thomas Münzel,Andreas Ziegler,Stefan Blankenberg +88 more
TL;DR: A genome-wide association and global gene expression study to identify functionally relevant variants affecting the risk of coronary artery disease (CAD) led to the identification of the novel functional CAD susceptibility locus LIPA, located on chromosome 10q23.31.