C
Christopher J. Fields
Researcher at University of Illinois at Urbana–Champaign
Publications - 79
Citations - 5026
Christopher J. Fields is an academic researcher from University of Illinois at Urbana–Champaign. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 24, co-authored 68 publications receiving 3887 citations. Previous affiliations of Christopher J. Fields include National Center for Supercomputing Applications & Urbana University.
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The Sanger FASTQ file format for sequences with quality scores, and the Solexa/Illumina FASTQ variants
TL;DR: The FASTQ format is defined, covering the original Sanger standard, the Solexa/Illumina variants and conversion between them, based on publicly available information such as the MAQ documentation and conventions recently agreed by the Open Bioinformatics Foundation projects Biopython, BioPerl, BioRuby, BioJava and EMBOSS.
SURVEY AND SUMMARY The Sanger FASTQ file format for sequences with quality scores, and the Solexa/Illumina FASTQ variants
TL;DR: FASTQ has emerged as a common file format for sharing sequencing read data combining both the sequence and an associated per base quality score, despite lacking any formal definition to date, and existing in at least three incompatible variants as mentioned in this paper.
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Plasma Exosomal miRNAs in Persons with and without Alzheimer Disease: Altered Expression and Prospects for Biomarkers
Giovanni Lugli,Aaron Cohen,David A. Bennett,Raj C. Shah,Christopher J. Fields,Alvaro G. Hernandez,Neil R. Smalheiser +6 more
TL;DR: The findings warrant replication and follow-up with a larger cohort of patients and controls who have been carefully characterized in terms of cognitive and imaging data, other biomarkers and risk factors, and who are sampled repeatedly over time.
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Exercise and the Gut Microbiome: A Review of the Evidence, Potential Mechanisms, and Implications for Human Health
TL;DR: In this paper, the authors reviewed what is known about the gut microbiota, how it is studied, and how it was influenced by exercise training and discussed the potential mechanisms and implications for human health and disease.
Journal ArticleDOI
Adaptation to deep-sea chemosynthetic environments as revealed by mussel genomes
Jin Sun,Jin Sun,Yu Zhang,Ting Xu,Yang Zhang,Huawei Mu,Yanjie Zhang,Yi Lan,Christopher J. Fields,Jerome H.L. Hui,Weipeng Zhang,Runsheng Li,Wenyan Nong,Fiona K.M. Cheung,Jian-Wen Qiu,Pei-Yuan Qian +15 more
TL;DR: The genomes of a deep-sea vent/seep mussel and a shallow-water mussel are reported, revealing presumed genetic adaptation of theDeep-sea mussel to the presence of its chemoautotrophic endosymbionts and wider insights into the mechanisms of symbiosis in other organisms such as deep- sea tubeworms and giant clams are given.