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Christopher W. Botka
Researcher at Harvard University
Publications - 4
Citations - 1505
Christopher W. Botka is an academic researcher from Harvard University. The author has contributed to research in topics: Turtle (robot) & Genome. The author has an hindex of 4, co-authored 4 publications receiving 1413 citations.
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Journal ArticleDOI
The genome of the green anole lizard and a comparative analysis with birds and mammals
Jessica Alföldi,Federica Di Palma,Manfred Grabherr,Christina L. Williams,Lesheng Kong,Evan Mauceli,Pamela Russell,Craig B. Lowe,Richard E. Glor,Jacob D. Jaffe,David A. Ray,Stéphane Boissinot,Andrew M. Shedlock,Christopher W. Botka,Todd A. Castoe,John K. Colbourne,Matthew K. Fujita,Matthew K. Fujita,Ricardo Moreno,Boudewijn F.H. Ten Hallers,David Haussler,Andreas Heger,David I. Heiman,Daniel E. Janes,Jeremy A. Johnson,Pieter J. de Jong,Maxim Koriabine,Marcia Lara,Peter A. Novick,Chris L. Organ,Sally E. Peach,Steven Poe,David D. Pollock,Kevin de Queiroz,Thomas J. Sanger,Steve Searle,Jeremy Smith,Zachary Smith,Ross Swofford,Jason Turner-Maier,Juli Wade,Sarah Young,Amonida Zadissa,Scott V. Edwards,Travis C. Glenn,Christopher J. Schneider,Jonathan B. Losos,Eric S. Lander,Matthew Breen,Matthew Breen,Chris P. Ponting,Kerstin Lindblad-Toh,Kerstin Lindblad-Toh +52 more
TL;DR: Comparative gene analysis shows that amniote egg proteins have evolved significantly more rapidly than other proteins, and an anole phylogeny resolves basal branches to illuminate the history of their repeated adaptive radiations.
The genome of the green anole lizard and a comparative analysis with birds and mammals
Jessica Alföldi,Federica Di Palma,Manfred Grabherr,Christina L. Williams,Lesheng Kong,Evan Mauceli,Pamela Russell,Craig B. Lowe,Richard E. Glor,Jacob D. Jaffe,David A. Ray,Stéphane Boissinot,Andrew M. Shedlock,Christopher W. Botka,Todd A. Castoe,John K. Colbourne,Matthew K. Fujita,Matthew K. Fujita,Ricardo Moreno,Boudewijn F.H. Ten Hallers,David Haussler,Andreas Heger,David I. Heiman,Daniel E. Janes,Jeremy A. Johnson,Pieter J. de Jong,Maxim Koriabine,Marcia Lara,Peter A. Novick,Chris L. Organ,Sally E. Peach,Steven Poe,David D. Pollock,Kevin de Queiroz,Thomas J. Sanger,Steve Searle,Jeremy Smith,Zachary Smith,Ross Swofford,Jason Turner-Maier,Juli Wade,Sarah Young,Amonida Zadissa,Scott V. Edwards,Travis C. Glenn,Christopher J. Schneider,Jonathan B. Losos,Eric S. Lander,Matthew Breen,Matthew Breen,Chris P. Ponting,Kerstin Lindblad-Toh,Kerstin Lindblad-Toh +52 more
TL;DR: The evolution of the amniotic egg was one of the great evolutionary innovations in the history of life, freeing vertebrates from an obligatory connection to water and thus permitting the conquest of terrestrial environments as discussed by the authors.
Journal ArticleDOI
The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage
H. Bradley Shaffer,Patrick Minx,Daniel E. Warren,Andrew M. Shedlock,Andrew M. Shedlock,Robert C. Thomson,Nicole Valenzuela,John Abramyan,Chris T. Amemiya,Daleen Badenhorst,Kyle K. Biggar,Glen M. Borchert,Glen M. Borchert,Christopher W. Botka,Rachel M. Bowden,Edward L. Braun,Anne M. Bronikowski,Benoit G. Bruneau,Leslie T. Buck,Blanche Capel,Todd A. Castoe,Todd A. Castoe,Michael Czerwinski,Kim D. Delehaunty,Scott V. Edwards,Catrina Fronick,Matthew K. Fujita,Matthew K. Fujita,Lucinda Fulton,Tina Graves,Richard E. Green,Wilfried Haerty,Ramkumar Hariharan,Omar E. Hernandez,LaDeana W. Hillier,Alisha K. Holloway,Daniel E. Janes,Fredric J. Janzen,Cyriac Kandoth,Lesheng Kong,A. P. Jason de Koning,Yang I. Li,Robert Literman,Suzanne E. McGaugh,Lindsey Mork,Michelle O'Laughlin,Ryan T. Paitz,David D. Pollock,Chris P. Ponting,Srihari Radhakrishnan,Brian J. Raney,Joy M. Richman,John St. John,Tonia S. Schwartz,Arun Sethuraman,Phillip Q. Spinks,Kenneth B. Storey,Nay Thane,Tomas Vinar,Laura M. Zimmerman,Wesley C. Warren,Elaine R. Mardis,Richard K. Wilson +62 more
TL;DR: Common vertebrate regulatory networks, some of which have analogs in human diseases, are often involved in the western painted turtle's extraordinary physiological capacities, and may offer important insights into the management of a number of human health disorders.
Journal ArticleDOI
Phylogenomics of nonavian reptiles and the structure of the ancestral amniote genome
Andrew M. Shedlock,Christopher W. Botka,Shaying Zhao,Jyoti Shetty,Tingting Zhang,Jun Liu,Patrick Deschavanne,Scott V. Edwards +7 more
TL;DR: A megabase-scale phylogenomic analysis of the Reptilia suggests a diverse array of interspersed and SSRs in the common ancestor of amniotes and a genomic conservatism and gradual loss of retroelements in reptiles that culminated in the minimalist chicken genome.