F
Federica Di Palma
Researcher at University of East Anglia
Publications - 80
Citations - 28470
Federica Di Palma is an academic researcher from University of East Anglia. The author has contributed to research in topics: Genome & Genomics. The author has an hindex of 34, co-authored 68 publications receiving 22671 citations. Previous affiliations of Federica Di Palma include University of New Hampshire & Norwich Research Park.
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Journal ArticleDOI
Full-length transcriptome assembly from RNA-Seq data without a reference genome.
Manfred Grabherr,Brian J. Haas,Moran Yassour,Moran Yassour,Joshua Z. Levin,Dawn Thompson,Ido Amit,Xian Adiconis,Lin Fan,Raktima Raychowdhury,Qiandong Zeng,Zehua Chen,Evan Mauceli,Nir Hacohen,Andreas Gnirke,Nicholas Rhind,Federica Di Palma,Bruce W. Birren,Chad Nusbaum,Kerstin Lindblad-Toh,Kerstin Lindblad-Toh,Nir Friedman,Aviv Regev +22 more
TL;DR: The Trinity method for de novo assembly of full-length transcripts and evaluate it on samples from fission yeast, mouse and whitefly, whose reference genome is not yet available, providing a unified solution for transcriptome reconstruction in any sample.
Journal ArticleDOI
The genomic basis of adaptive evolution in threespine sticklebacks
Felicity C. Jones,Manfred Grabherr,Manfred Grabherr,Yingguang Frank Chan,Pamela Russell,Evan Mauceli,Evan Mauceli,Jeremy Johnson,Ross Swofford,Mono Pirun,Mono Pirun,Michael C. Zody,Simon D. M. White,Ewan Birney,Stephen M. J. Searle,Jeremy Schmutz,Jane Grimwood,Mark Dickson,Richard M. Myers,Craig Miller,Craig Miller,Brian R. Summers,Anne K. Knecht,Shannon D. Brady,Haili Zhang,Alex A. Pollen,Timothy R. Howes,Chris T. Amemiya,Eric S. Lander,Federica Di Palma,Kerstin Lindblad-Toh,Kerstin Lindblad-Toh,David M. Kingsley,David M. Kingsley +33 more
TL;DR: A high-quality reference genome assembly for threespine stickleback fish is developed and it is indicated that reuse of globally shared standing genetic variation has an important role in repeated evolution of distinct marine and freshwater sticklebacks, and in the maintenance of divergent ecotypes during early stages of reproductive isolation.
The genomic basis of adaptive evolution in threespine sticklebacks
Felicity C. Jones,Manfred Grabherr,Yingguang Frank Chan,Pamela Russell,Evan Mauceli,Jeremy A. Johnson,Ross Swofford,Mono Pirun,Michael C. Zody,Simon D. M. White,Ewan Birney,Stephen M. J. Searle,Jeremy Schmutz,Jane Grimwood,Mark Dickson,Richard M. Myers,Craig Miller,Brian R. Summers,Anne K. Knecht,Shannon D. Brady,Haili Zhang,Alex A. Pollen,Timothy R. Howes,Chris T. Amemiya,Jen Baldwin,Toby Bloom,David B. Jaffe,Robert Nicol,Jane E. Wilkinson,Eric S. Lander,Federica Di Palma,Kerstin Lindblad-Toh,David M. Kingsley +32 more
Journal ArticleDOI
A high-resolution map of human evolutionary constraint using 29 mammals.
Kerstin Lindblad-Toh,Manuel Garber,Or Zuk,Michael F. Lin,Michael F. Lin,Brian J. Parker,Stefan Washietl,Pouya Kheradpour,Pouya Kheradpour,Jason Ernst,Jason Ernst,Gregory E. Jordan,Evan Mauceli,Lucas D. Ward,Lucas D. Ward,Craig B. Lowe,Craig B. Lowe,Craig B. Lowe,Alisha K. Holloway,Michele Clamp,Sante Gnerre,Jessica Alföldi,Kathryn Beal,Jean Chang,Hiram Clawson,James Cuff,Federica Di Palma,Stephen Fitzgerald,Paul Flicek,Mitchell Guttman,Melissa J. Hubisz,David B. Jaffe,Irwin Jungreis,W. James Kent,Dennis Kostka,Marcia Lara,André L. Martins,Tim Massingham,Ida Moltke,Brian J. Raney,Matthew D. Rasmussen,James Robinson,Alexander Stark,Albert J. Vilella,Jiayu Wen,Xiaohui Xie,Michael C. Zody,Kim C. Worley,Christie Kovar,Donna M. Muzny,Richard A. Gibbs,Wesley C. Warren,Elaine R. Mardis,George M. Weinstock,George M. Weinstock,Richard K. Wilson,Ewan Birney,Elliott H. Margulies,Javier Herrero,Eric D. Green,David Haussler,David Haussler,Adam Siepel,Nick Goldman,Katherine S. Pollard,Jakob Skou Pedersen,Jakob Skou Pedersen,Eric S. Lander,Manolis Kellis,Manolis Kellis +69 more
TL;DR: The comparison of related genomes has emerged as a powerful lens for genome interpretation and sequencing and comparative analysis of 29 eutherian genomes confirm that at least 5.5% of the human genome has undergone purifying selection, and locate constrained elements covering ∼4.2%" of the genome.
Journal ArticleDOI
The genomic substrate for adaptive radiation in African cichlid fish
David Brawand,David Brawand,Catherine E. Wagner,Catherine E. Wagner,Yang I. Li,Milan Malinsky,Milan Malinsky,Irene Keller,Shaohua Fan,Oleg Simakov,Alvin Yu Jin Ng,Zhi Wei Lim,Etienne Bezault,Jason Turner-Maier,Jeremy A. Johnson,Rosa Alcazar,Hyun Ji Noh,Pamela Russell,Bronwen Aken,Jessica Alföldi,Chris T. Amemiya,Naoual Azzouzi,Jean-François Baroiller,Frédérique Barloy-Hubler,Aaron M. Berlin,Ryan F. Bloomquist,Karen L. Carleton,Matthew A. Conte,Helena D'Cotta,Orly Eshel,Leslie Gaffney,Francis Galibert,Hugo F. Gante,Sante Gnerre,Lucie Greuter,Lucie Greuter,Richard Guyon,Natalie S. Haddad,Wilfried Haerty,Robert M Harris,Hans A. Hofmann,Thibaut Hourlier,Gideon Hulata,David B. Jaffe,Marcia Lara,Alison P. Lee,Iain MacCallum,Salome Mwaiko,Masato Nikaido,Hidenori Nishihara,Catherine Ozouf-Costaz,David J. Penman,Dariusz Przybylski,Michaelle Rakotomanga,Suzy C. P. Renn,Filipe J. Ribeiro,Micha Ron,Walter Salzburger,Luis Sanchez-Pulido,M. Emília Santos,Steve Searle,Ted Sharpe,Ross Swofford,Frederick J. Tan,Louise Williams,Sarah Young,Shuangye Yin,Norihiro Okada,Norihiro Okada,Thomas D. Kocher,Eric A. Miska,Eric S. Lander,Byrappa Venkatesh,Russell D. Fernald,Axel Meyer,Chris P. Ponting,J. Todd Streelman,Kerstin Lindblad-Toh,Kerstin Lindblad-Toh,Ole Seehausen,Ole Seehausen,Federica Di Palma,Federica Di Palma +82 more
TL;DR: This article found an excess of gene duplications in the East African lineage compared to Nile tilapia and other teleosts, an abundance of non-coding element divergence, accelerated coding sequence evolution, expression divergence associated with transposable element insertions, and regulation by novel microRNAs.