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Pamela Russell
Researcher at Colorado School of Public Health
Publications - 37
Citations - 8777
Pamela Russell is an academic researcher from Colorado School of Public Health. The author has contributed to research in topics: Medicine & Metadata. The author has an hindex of 20, co-authored 32 publications receiving 7826 citations. Previous affiliations of Pamela Russell include University of Colorado Denver & Anschutz Medical Campus.
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Journal ArticleDOI
The genomic basis of adaptive evolution in threespine sticklebacks
Felicity C. Jones,Manfred Grabherr,Manfred Grabherr,Yingguang Frank Chan,Pamela Russell,Evan Mauceli,Evan Mauceli,Jeremy Johnson,Ross Swofford,Mono Pirun,Mono Pirun,Michael C. Zody,Simon D. M. White,Ewan Birney,Stephen M. J. Searle,Jeremy Schmutz,Jane Grimwood,Mark Dickson,Richard M. Myers,Craig Miller,Craig Miller,Brian R. Summers,Anne K. Knecht,Shannon D. Brady,Haili Zhang,Alex A. Pollen,Timothy R. Howes,Chris T. Amemiya,Eric S. Lander,Federica Di Palma,Kerstin Lindblad-Toh,Kerstin Lindblad-Toh,David M. Kingsley,David M. Kingsley +33 more
TL;DR: A high-quality reference genome assembly for threespine stickleback fish is developed and it is indicated that reuse of globally shared standing genetic variation has an important role in repeated evolution of distinct marine and freshwater sticklebacks, and in the maintenance of divergent ecotypes during early stages of reproductive isolation.
The genomic basis of adaptive evolution in threespine sticklebacks
Felicity C. Jones,Manfred Grabherr,Yingguang Frank Chan,Pamela Russell,Evan Mauceli,Jeremy A. Johnson,Ross Swofford,Mono Pirun,Michael C. Zody,Simon D. M. White,Ewan Birney,Stephen M. J. Searle,Jeremy Schmutz,Jane Grimwood,Mark Dickson,Richard M. Myers,Craig Miller,Brian R. Summers,Anne K. Knecht,Shannon D. Brady,Haili Zhang,Alex A. Pollen,Timothy R. Howes,Chris T. Amemiya,Jen Baldwin,Toby Bloom,David B. Jaffe,Robert Nicol,Jane E. Wilkinson,Eric S. Lander,Federica Di Palma,Kerstin Lindblad-Toh,David M. Kingsley +32 more
Journal ArticleDOI
The genomic substrate for adaptive radiation in African cichlid fish
David Brawand,David Brawand,Catherine E. Wagner,Catherine E. Wagner,Yang I. Li,Milan Malinsky,Milan Malinsky,Irene Keller,Shaohua Fan,Oleg Simakov,Alvin Yu Jin Ng,Zhi Wei Lim,Etienne Bezault,Jason Turner-Maier,Jeremy A. Johnson,Rosa Alcazar,Hyun Ji Noh,Pamela Russell,Bronwen Aken,Jessica Alföldi,Chris T. Amemiya,Naoual Azzouzi,Jean-François Baroiller,Frédérique Barloy-Hubler,Aaron M. Berlin,Ryan F. Bloomquist,Karen L. Carleton,Matthew A. Conte,Helena D'Cotta,Orly Eshel,Leslie Gaffney,Francis Galibert,Hugo F. Gante,Sante Gnerre,Lucie Greuter,Lucie Greuter,Richard Guyon,Natalie S. Haddad,Wilfried Haerty,Robert M Harris,Hans A. Hofmann,Thibaut Hourlier,Gideon Hulata,David B. Jaffe,Marcia Lara,Alison P. Lee,Iain MacCallum,Salome Mwaiko,Masato Nikaido,Hidenori Nishihara,Catherine Ozouf-Costaz,David J. Penman,Dariusz Przybylski,Michaelle Rakotomanga,Suzy C. P. Renn,Filipe J. Ribeiro,Micha Ron,Walter Salzburger,Luis Sanchez-Pulido,M. Emília Santos,Steve Searle,Ted Sharpe,Ross Swofford,Frederick J. Tan,Louise Williams,Sarah Young,Shuangye Yin,Norihiro Okada,Norihiro Okada,Thomas D. Kocher,Eric A. Miska,Eric S. Lander,Byrappa Venkatesh,Russell D. Fernald,Axel Meyer,Chris P. Ponting,J. Todd Streelman,Kerstin Lindblad-Toh,Kerstin Lindblad-Toh,Ole Seehausen,Ole Seehausen,Federica Di Palma,Federica Di Palma +82 more
TL;DR: This article found an excess of gene duplications in the East African lineage compared to Nile tilapia and other teleosts, an abundance of non-coding element divergence, accelerated coding sequence evolution, expression divergence associated with transposable element insertions, and regulation by novel microRNAs.
The genomic substrate for adaptive radiation in African cichlid fish
David Brawand,David Brawand,Catherine E. Wagner,Catherine E. Wagner,Yang I. Li,Milan Malinsky,Milan Malinsky,Irene Keller,Shaohua Fan,Oleg Simakov,Alvin Yu Jin Ng,Zhi Wei Lim,Etienne Bezault,Jason Turner-Maier,Jeremy A. Johnson,Rosa Alcazar,Hyun Ji Noh,Pamela Russell,Bronwen Aken,Jessica Alföldi,Chris T. Amemiya,Naoual Azzouzi,Jean-François Baroiller,Frédérique Barloy-Hubler,Aaron M. Berlin,Ryan F. Bloomquist,Karen L. Carleton,Matthew A. Conte,Helena D'Cotta,Orly Eshel,Leslie Gaffney,Francis Galibert,Hugo F. Gante,Sante Gnerre,Lucie Greuter,Lucie Greuter,Richard Guyon,Natalie S. Haddad,Wilfried Haerty,Robert M Harris,Hans A. Hofmann,Thibaut Hourlier,Gideon Hulata,David B. Jaffe,Marcia Lara,Alison P. Lee,Iain MacCallum,Salome Mwaiko,Masato Nikaido,Hidenori Nishihara,Catherine Ozouf-Costaz,David J. Penman,Dariusz Przybylski,Michaelle Rakotomanga,Suzy C. P. Renn,Filipe J. Ribeiro,Micha Ron,Walter Salzburger,Luis Sanchez-Pulido,M. Emília Santos,Steve Searle,Ted Sharpe,Ross Swofford,Frederick J. Tan,Louise Williams,Sarah Young,Shuangye Yin,Norihiro Okada,Norihiro Okada,Thomas D. Kocher,Eric A. Miska,Eric S. Lander,Byrappa Venkatesh,Russell D. Fernald,Axel Meyer,Chris P. Ponting,J. Todd Streelman,Kerstin Lindblad-Toh,Kerstin Lindblad-Toh,Ole Seehausen,Ole Seehausen,Federica Di Palma,Federica Di Palma +82 more
TL;DR: It is concluded that a number of molecular mechanisms shaped East African cichlid genomes, and that amassing of standing variation during periods of relaxed purifying selection may have been important in facilitating subsequent evolutionary diversification.
Ribosome Profiling Provides Evidence that Large Noncoding RNAs Do Not Encode Proteins
Mitchell Guttman,Pamela Russell,Nicholas T. Ingolia,Jonathan S. Weissman,Eric S. Lander,Eric S. Lander,Eric S. Lander +6 more
TL;DR: It is shown that classical noncoding RNAs and 5' UTRs show the same ribosomes occupancy as lincRNAs, demonstrating that ribosome occupancy alone is not sufficient to classify transcripts as coding or nonc coding.