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Cindy B. Matsen
Researcher at University of Utah
Publications - 48
Citations - 2186
Cindy B. Matsen is an academic researcher from University of Utah. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 14, co-authored 40 publications receiving 1786 citations. Previous affiliations of Cindy B. Matsen include University of Oregon & Government of the United States of America.
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Journal ArticleDOI
Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes
Yoko S. DeRose,Guoying Wang,Yi Chun Lin,Philip S. Bernard,Saundra S. Buys,Mark T. W. Ebbert,Rachel E. Factor,Cindy B. Matsen,Brett Milash,Edward W. Nelson,Leigh Neumayer,R. Lor Randall,Inge J. Stijleman,Bryan E. Welm,Alana L. Welm +14 more
TL;DR: It is reported that tumor engraftment is a prognostic indicator of disease outcome for women with newly diagnosed breast cancer and orthotopic breast tumor grafting is a step toward individualized models for tumor growth, metastasis and prognosis.
Journal ArticleDOI
Inhibition of DNA Methylation and Reactivation of Silenced Genes by Zebularine
Jonathan C. Cheng,Cindy B. Matsen,Felicidad A. Gonzales,Wei Ye,Sheldon Greer,Victor E. Marquez,Peter A. Jones,Eric U. Selker +7 more
TL;DR: Zebularine is a stable DNA demethylating agent and the first drug in its class able to reactivate an epigenetically silenced gene by oral administration.
Journal ArticleDOI
Breast Cancer: A Review for the General Surgeon
Cindy B. Matsen,Leigh Neumayer +1 more
TL;DR: It is highlighted that the surgical management of breast cancer has changed dramatically over the past decades, and as the understanding of the disease process increases, practice guidelines will continue to evolve.
Journal ArticleDOI
Skin Flap Necrosis After Mastectomy With Reconstruction: A Prospective Study.
Cindy B. Matsen,Babak J. Mehrara,Anne Eaton,Deborah Capko,Anastasia Berg,Michelle Stempel,Kimberly J. Van Zee,Andrea L. Pusic,Tari A. King,Hiram S. Cody,Melissa Pilewskie,Peter G. Cordeiro,Lisa M. Sclafani,George Plitas,Mary L. Gemignani,Joseph J. Disa,Mahmoud El-Tamer,Monica Morrow +17 more
TL;DR: Rates of skin flap necrosis are likely higher than reported in retrospective series, and patients with multiple risk factors should be counseled about the risks, especially if they are contemplating nipple-sparing mastectomy.
Journal ArticleDOI
A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology
Katrin P. Guillen,Maihi Fujita,Andrew Butterfield,Sandra D. Scherer,Matthew A. Bailey,Zheng-Qing Chu,Yoko S. DeRose,Ling Zhao,Emilio Cortes-Sanchez,Chieh-Hsiang Yang,J. Toner,Guoying Wang,Yi Qiao,Xiaomeng Huang,Jeff Greenland,Jeffery M. Vahrenkamp,David H. Lum,Rachel E. Factor,Edward W. Nelson,Cindy B. Matsen,J. M. Poretta,Regina Rosenthal,Anna C. Beck,Saundra S. Buys,Christos Vaklavas,John Harris Ward,Randy L. Jensen,Kevin B. Jones,Zheqi Li,Steffi Oesterreich,Lacey E. Dobrolecki,Satya Pathi,Xing Yi Woo,Kristofer C. Berrett,Mark E. Wadsworth,Jeffrey H. Chuang,Michael Lewis,Gabor T. Marth,Jay Gertz,Katherine E. Varley,Bryan E. Welm,Alana L. Welm +41 more
TL;DR: In this article , a bank of human patient-derived xenografts and matched organoid cultures from tumors that represent the greatest unmet need: endocrine-resistant, treatment-refractory and metastatic breast cancers are reported.