Clare Bryce

TL;DR: Observations of virus in neural tissue, in conjunction with clinical correlates of worsening neurologic symptoms, pave the way to a closer understanding of the pathogenic mechanisms underlying central nervous system involvement by SARS‐CoV‐2.

TL;DR: COVID-19 pneumonia is a heterogeneous disease (tracheobronchitis, DAD, and vascular injury), but with consistent features in three centers, with Viral infection in areas of ongoing active injury contributes to persistent and temporally heterogeneous lung damage.

TL;DR: Novel findings reported here include an endothelial phenotype of ACE2 in selected organs, which correlates with clotting abnormalities and thrombotic microangiopathy, addressing the prominent coagulopathy and neuropsychiatric symptoms.

TL;DR: The first 100 COVID-19-positive autopsies performed at the Mount Sinai Hospital in New York City revealed large pulmonary emboli in six cases and diffuse alveolar damage was present in over 90% of cases as mentioned in this paper.

TL;DR: A systematic meta-analysis of histopathologic observations to date is conducted and the reported findings are reviewed to gain a better understanding of disease pathophysiology and its ongoing impact on public health.