L
Li Li
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 53
Citations - 3300
Li Li is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 20, co-authored 50 publications receiving 2524 citations. Previous affiliations of Li Li include Thomas Jefferson University Hospital & The Mount.
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Journal ArticleDOI
Deep Patient: An Unsupervised Representation to Predict the Future of Patients from the Electronic Health Records
TL;DR: The findings indicate that deep learning applied to EHRs can derive patient representations that offer improved clinical predictions, and could provide a machine learning framework for augmenting clinical decision systems.
Journal ArticleDOI
Identification of type 2 diabetes subgroups through topological analysis of patient similarity
Li Li,Wei-Yi Cheng,Benjamin S. Glicksberg,Omri Gottesman,Ronald Tamler,Rong Chen,Erwin P. Bottinger,Joel T. Dudley +7 more
TL;DR: The authors found that classical T2D features such as obesity, high blood sugar, kidney disease, and eye disease, were limited to subtype 1, whereas other comorbidities such as cancer and neurological diseases were specific to subtypes 2 and 3, respectively.
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AKI in hospitalized patients with COVID-19
Lili Chan,Kumardeep Chaudhary,Aparna Saha,Kinsuk Chauhan,Akhil Vaid,Shan Zhao,Ishan Paranjpe,Sulaiman Somani,Felix Richter,Riccardo Miotto,Anuradha Lala,Arash Kia,Prem Timsina,Li Li,Robert Freeman,Rong Chen,Jagat Narula,Allan C. Just,Carol R. Horowitz,Zahi A. Fayad,Carlos Cordon-Cardo,Eric E. Schadt,Matthew A. Levin,David Reich,Valentin Fuster,Barbara Murphy,John Cijiang He,Alexander W. Charney,Erwin P. Bottinger,Benjamin S. Glicksberg,Steven G. Coca,Girish N. Nadkarni +31 more
TL;DR: This retrospective, observational study involved a review of data from electronic health records of patients aged ≥18 years with laboratory-confirmed COVID-19 admitted to the Mount Sinai Health System from February 27 to May 30, 2020 to describe the frequency of AKI and dialysis requirement, AKI recovery, and adjusted odds ratios with mortality.
Posted ContentDOI
Pathophysiology of SARS-CoV-2: targeting of endothelial cells renders a complex disease with thrombotic microangiopathy and aberrant immune response. The Mount Sinai COVID-19 autopsy experience
Clare Bryce,Zachary Grimes,Elisabet Pujadas,Sadhna Ahuja,Mary Beth Beasley,Randy A. Albrecht,Hernandez T,Aryeh Stock,Zhen Zhao,Al Rasheed M,Jia Chen,Li Li,Wang D,Corben A,Haines K,William H. Westra,Melissa Umphlett,Ronald E. Gordon,Jason Reidy,Bruce Petersen,Fadi Salem,Maria Isabel Fiel,El Jamal Sm,Nadejda M. Tsankova,Jane Houldsworth,Zarmeen Mussa,Liu W,Veremis B,Emilia Mia Sordillo,Melissa R. Gitman,Michael D. Nowak,Rachel Brody,Noam Harpaz,Miriam Merad,Sacha Gnjatic,Ryan Donnelly,Seigler P,Keys C,Cameron J,Moultrie I,Washington K,Treatman J,Robert Sebra,Jeffrey S. Jhang,Adolfo Firpo,John A. Lednicky,Alberto Paniz-Mondolfi,Carlos Cordon-Cardo,Mary Fowkes +48 more
TL;DR: Novel findings reported here include an endothelial phenotype of ACE2 in selected organs, which correlates with clotting abnormalities and thrombotic microangiopathy, addressing the prominent coagulopathy and neuropsychiatric symptoms.
Journal ArticleDOI
AILUN: reannotating gene expression data automatically.
TL;DR: A fully automated system to reannotate all types of microarrays in GEO periodically by relating every probe identifier to Entrez Gene identifiers, and successfully reannotated 66% gene expression platforms, allowing reuse of 77% of samples across 79 species.