C
Clark T. Riley
Researcher at Johns Hopkins University School of Medicine
Publications - 6
Citations - 1087
Clark T. Riley is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Edman degradation & Pheromone biosynthesis activating neuropeptide. The author has an hindex of 5, co-authored 6 publications receiving 1064 citations.
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Journal ArticleDOI
Characterization of Protein Kinase A and Protein Kinase C Phosphorylation of the N-Methyl-D-aspartate Receptor NR1 Subunit Using Phosphorylation Site-specific Antibodies
Whittemore G. Tingley,Michael D. Ehlers,Kimihiko Kameyama,Carol A. Doherty,Janine Ptak,Clark T. Riley,Richard L. Huganir +6 more
TL;DR: It is demonstrated that PKA and PKC phosphorylate distinct residues within a small region of the NR1 sub unit and differentially affect the subcellular distribution of theNR1 subunit.
Journal ArticleDOI
Identification of a neuropeptide hormone that regulates sex pheromone production in female moths.
Ashok K. Raina,Howard Jaffe,Thomas G. Kempe,P. Keim,R. W. Blacher,Henry M. Fales,Clark T. Riley,Jerome A. Klun,R. L. Ridgway,D. K. Hayes +9 more
TL;DR: A pheromone biosynthesis activating neuropeptide (PBAN) hormone was identified from the brain-subesophageal ganglion complexes of the adult corn earworm, Heliothis zea, and induced production of a normal quantity of sex pherOMone in ligated H. zea females, indicating that this or similar peptides may be responsible for the regulation of phersomone production in moths.
Journal ArticleDOI
Isolation and primary structure of a peptide from the corpora cardiaca of Heliothis zea with adipokinetic activity.
Howard Jaffe,A K Raina,Clark T. Riley,B A Fraser,G M Holman,R.M. Wagner,R. L. Ridgway,D. K. Hayes +7 more
TL;DR: An adipokinetic hormone was isolated from the corpora cardiaca of the corn ear worm moth, Heliothis zea, and purified by reversed phase high performance liquid chromatography and found to have lipid mobilizing activity in H. zea adults.
Journal ArticleDOI
Isolation and primary structure of a neuropeptide hormone from Heliothis zea with hypertrehalosemic and adipokinetic activities.
Howard Jaffe,Ashok K. Raina,Clark T. Riley,Blair Fraser,Thomas G. Bird,Ching-Ming Tseng,Yao-Shi Zhang,D. K. Hayes +7 more
TL;DR: The hormone was synthesized and the natural and synthetic peptides had identical chromatographic and spectroscopic properties and caused the elevation of trehalose and lipid levels in the hemolymph of adult H. zea males.
Journal ArticleDOI
Primary structure of two neuropeptide hormones with adipokinetic and hypotrehalosemic activity isolated from the corpora cardiaca of horse flies (Diptera)
Howard Jaffe,Ashok K. Raina,Clark T. Riley,Blair Fraser,Ronald J. Nachman,Van W. Vogel,Yao-Shi Zhang,D. K. Hayes +7 more
TL;DR: The primary structures of two neuropeptides, Tabanus atratus adipokinetic hormone (Taa-AKH) and Taa-HoTH, from the corpora cardiaca of horse flies have been determined and the natural and synthetic peptides exhibited identical chromatographic, spectroscopic, and biological properties.