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Daniela Vecchio
Researcher at Harvard University
Publications - 38
Citations - 3181
Daniela Vecchio is an academic researcher from Harvard University. The author has contributed to research in topics: Hepatic stellate cell & Oxidative stress. The author has an hindex of 24, co-authored 38 publications receiving 2614 citations. Previous affiliations of Daniela Vecchio include University of Siena.
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Journal ArticleDOI
Antimicrobial strategies centered around reactive oxygen species - bactericidal antibiotics, photodynamic therapy and beyond
Fatma Vatansever,Wanessa C.M.A. de Melo,Wanessa C.M.A. de Melo,Pinar Avci,Pinar Avci,Daniela Vecchio,Magesh Sadasivam,Magesh Sadasivam,Asheesh Gupta,Asheesh Gupta,Rakkiyappan Chandran,Rakkiyappan Chandran,Mahdi Karimi,Mahdi Karimi,Nivaldo Antonio Parizotto,Rui Yin,Rui Yin,George P. Tegos,Michael R. Hamblin,Michael R. Hamblin +19 more
TL;DR: Antioxidant defenses against ROS in microbial cells and the use of ROS by antimicrobial host defense systems are covered and reactive nitrogen species and related therapeutics, such as acidified nitrite and nitric oxide-releasing nanoparticles are covered.
Journal Article
Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring.
Pinar Avci,Asheesh Gupta,Magesh Sadasivam,Daniela Vecchio,Zeev Pam,Nadav Pam,Michael R. Hamblin +6 more
TL;DR: Low-level laser (light) therapy (LLLT) is a fast-growing technology used to treat a multitude of conditions that require stimulation of healing, relief of pain and inflammation, and restoration of function.
Journal ArticleDOI
Light based anti-infectives: ultraviolet C irradiation, photodynamic therapy, blue light, and beyond.
Rui Yin,Tianhong Dai,Pinar Avci,Pinar Avci,Ana Elisa Serafim Jorge,Ana Elisa Serafim Jorge,Wanessa C.M.A. de Melo,Wanessa C.M.A. de Melo,Daniela Vecchio,Ying-Ying Huang,Ying-Ying Huang,Asheesh Gupta,Asheesh Gupta,Michael R. Hamblin,Michael R. Hamblin +14 more
TL;DR: Photodynamic therapy is the combination of non-toxic photosensitizing dyes with harmless visible light that together produce abundant destructive reactive oxygen species (ROS) and has good specificity for binding to microbial cells while sparing host mammalian cells and can be used for treating many localized infections.
Journal ArticleDOI
Ethanol-induced oxidative stress: basic knowledge
Mario Comporti,Cinzia Signorini,Silvia Leoncini,Concetta Gardi,Lucia Ciccoli,Anna Giardini,Daniela Vecchio,Beatrice Arezzini +7 more
TL;DR: The ethanol-induced lipid peroxidation has been evaluated, and it has been shown that plasma F2-isoprostanes are increased in ethanol toxicity.
Journal ArticleDOI
Photodynamic inactivation of biofilm: taking a lightly colored approach to stubborn infection
Wanessa C.M.A. de Melo,Pinar Avci,Milene Nóbrega de Oliveira,Asheesh Gupta,Daniela Vecchio,Magesh Sadasivam,Rakkiyappan Chandran,Ying-Ying Huang,Rui Yin,Livia Rodrigues Perussi,George P. Tegos,Janice Rodrigues Perussi,Tianhong Dai,Michael R. Hamblin +13 more
TL;DR: Antimicrobial photodynamic therapy (aPDT) as discussed by the authors involves the combination of a nontoxic dye and low-intensity visible light which produces cytotoxic reactive oxygen species.