Costantino Iadecola

TL;DR: The findings show that AG decreases ischemic brain damage dose-dependently and improves neurologic recovery and delayed treatment with AG may be a therapeutic strategy to selectively target the evolution of isChemic damage that occurs in the post-ischemic period.

TL;DR: It is found that activation of nuclear factor-κB, a transcription factor that coordinates postischemic gene expression, is attenuated in CD36-null mice subjected to middle cerebral artery occlusion, andhibition of CD36 signaling may be a valuable therapeutic approach to counteract the deleterious effects of postISChemic inflammation.

TL;DR: The role of glutamate, GABA, nitric oxide (NO) and adenosine in the increases in cerebellar cortex blood flow (BFcrb) elicited by PF stimulation is studied.

TL;DR: PSVT seems to be a novel risk factor that may account for some proportion of strokes that are currently classified as cryptogenic, and in a large and demographically diverse sample of patients, an independent association between PSVT and ischemic stroke is found.

TL;DR: The RVM contains a well-defined group of neurons endowed with NOS that are distinct from the adrenergic neurons of the C1 group and have only limited monosynaptic projections to the spinal cord, raising the possibility that nitric oxide participates in central autonomic regulation and oxygen chemoreception.