Costantino Iadecola

TL;DR: FN stimulation, unlike hypercapnia, increases CBF to the ischemic cortex, improves recovery of electrical activity, and reduces tissue damage after MCA occlusion, and these findings support the hypothesis that FN stimulation reduces isChemic damage by enhancing collateral flow to theIschemic territory.

TL;DR: The data suggest that the sexual dimorphism in AngII‐induced hypertension is associated with sex differences in ROS production in AT1aR‐containing PVN cells but not with postsynaptic NMDA receptor trafficking.

TL;DR: Results indicate that NADPH oxidase assembly and consequent superoxide formation are likely to occur near the plasmalemma, as well as on vesicular organelles associated with intracellular calcium storage within mNTS neurons and glia, and NADPH oxidation-derived superoxide in neurons andglia may directly or indirectly modulate catecholaminergic neuron activity in the mN TS.

TL;DR: It is demonstrated that prohibitin overexpression protects highly vulnerable CA1 neurons from ischemic injury in vivo and suggested that the effect is mediated by reduction of postischemic reactive oxygen species generation and preservation of mitochondrial outer membrane integrity that prevents activation of apoptosis.

TL;DR: Adult patients discharged from nonfederal acute care hospitals in California, New York, and Florida who underwent surgical or endovascular repair of an aortic aneurysm or dissection between 2005 and 2013 are identified to estimate crude rates of spinal cord infarction (SCI).