Cristina Siegerist

TL;DR: The hypothesis that bacteria from phyla lacking cultivated representatives are small and thus might be enriched by filtration for coupled genomic and ultrastructural characterization is tested.

TL;DR: 3D cryogenic electron tomography is used to determine the size and ultrastructure of intact ARMAN cells, a novel ultra-small archaeon, and seek evidence for their interactions with other members of its community, providing the first 3D analysis of structural features of these novel and enigmatic cells.

TL;DR: Cryo-EM images of bacteriophage that had packaged defined fragments of the genome as well as particles that had partially completed the packaging process shows that there is no unique, deterministic DNA packaging pathway.

TL;DR: The LBNL/NERSC Visportal effort explores ways to deliver advanced Remote/Distributed Visualization capabilities through a Grid-enabled web-portal interface by leveraging commercially-supported technology as much as possible in order to create a deployable, supportable, and hence viable platform for delivering grid-based visualization services to collaboratory users.

TL;DR: A two-dimensional structural analysis of the expanding boundary of an isolated Lysinibacillus sphaericus S-layer (SbpA) growing on a graphene support is reported, revealing previously unknown steps in the conformational transformation that drives the well-documented non-classical pathway of S- layer assembly.