K
Kelly C. Wrighton
Researcher at Colorado State University
Publications - 117
Citations - 9618
Kelly C. Wrighton is an academic researcher from Colorado State University. The author has contributed to research in topics: Metagenomics & Biology. The author has an hindex of 38, co-authored 93 publications receiving 7032 citations. Previous affiliations of Kelly C. Wrighton include Planetary Science Institute & Ohio State University.
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Unusual biology across a group comprising more than 15% of domain Bacteria
Christopher T. Brown,Laura A. Hug,Brian C. Thomas,Itai Sharon,Cindy J. Castelle,Andrea Singh,Michael J. Wilkins,Kelly C. Wrighton,Kenneth H. Williams,Jillian F. Banfield +9 more
TL;DR: This work reconstructed 8 complete and 789 draft genomes from bacteria representing >35 phyla and documented features that consistently distinguish these organisms from other bacteria, infer that this group, which may comprise >15% of the bacterial domain, has shared evolutionary history, and describe it as the candidate phyla radiation (CPR).
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Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated bacterial phyla.
Kelly C. Wrighton,Brian C. Thomas,Itai Sharon,Christopher S. Miller,Cindy J. Castelle,Nathan C Verberkmoes,Michael J. Wilkins,Robert L. Hettich,Mary S. Lipton,Kenneth H. Williams,Philip E. Long,Jillian F. Banfield,Jillian F. Banfield +12 more
TL;DR: This article uncovered metabolic characteristics for members of these phyla, and a new lineage, PER, via cultivation-independent recovery of 49 partial to near-complete genomes from an acetate-amended aquifer.
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Experimental factors affecting PCR-based estimates of microbial species richness and evenness.
Anna Engelbrektson,Victor Kunin,Kelly C. Wrighton,Natasha Zvenigorodsky,Feng Chen,Howard Ochman,Philip Hugenholtz +6 more
TL;DR: The results show that both amplicon length and primer pair markedly influence estimates of richness and evenness, however, estimates of species evenness are consistent among different primer pairs targeting the same region, highlighting the importance of experimental methodology when comparing diversity estimates across communities.
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Genomic Expansion of Domain Archaea Highlights Roles for Organisms from New Phyla in Anaerobic Carbon Cycling
Cindy J. Castelle,Kelly C. Wrighton,Brian C. Thomas,Laura A. Hug,Christopher T. Brown,Michael J. Wilkins,Kyle R. Frischkorn,Susannah G. Tringe,Andrea Singh,Lye Meng Markillie,Ronald C. Taylor,Kenneth H. Williams,Jillian F. Banfield +12 more
TL;DR: This study sequenced DNA from complex sediment and planktonic consortia from an aquifer adjacent to the Colorado River and reconstructed the first complete genomes for Archaea using cultivation-independent methods, which dramatically expand genomic sampling of the domain Archaea and clarify taxonomic designations within a major superphylum.
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Community genomic analyses constrain the distribution of metabolic traits across the Chloroflexi phylum and indicate roles in sediment carbon cycling
Laura A. Hug,Cindy J. Castelle,Kelly C. Wrighton,Brian C. Thomas,Itai Sharon,Kyle R. Frischkorn,Kenneth H. Williams,Susannah G. Tringe,Jillian F. Banfield +8 more
TL;DR: The potential roles of Chloroflexi in sediment carbon cycling beyond organohalide respiration are expanded to include respiration of sugars, fermentation, CO2 fixation, and acetogenesis with ATP formation by substrate-level phosphorylation.