Csaba Nyakas

TL;DR: The distribution pattern and levels of expression of two estrogen receptor (ER) subtypes, ERα and ERβ, in the normal adult and aged female rat hippocampus are studied with the objective to establish baseline data and the changes that occur during aging.

TL;DR: In this study the neuroprotective effect of memantine on the forebrain cholinergic neurons against Aβ42 oligomers-induced toxicity was studied in an in vivo rat dementia model and it was found that memantine rescued the neocorticalcholinergic fibers originating from the basal forebrain dendritic neurons.

TL;DR: The findings indicate that neonatal dexamethasone treatment permanently alters HPA axis activity by reducing stress responses to cold and restraint probably through supra‐pituitary actions, and by decreasing the effectiveness of feedback through a diminished GR binding in the pituitary.

TL;DR: It is concluded that age of experimental animals is a factor worsening the outcome following brain ischemia and a single-dose estrogen therapy prevents the lesion-induced behavioural dysfunctions and the hippocampal cell loss.

TL;DR: The novel object recognition paradigm and the hole-board spatial learning test could reliably be added to the battery of conventional behavioural tests applied previously in this species to measure attention and learning capacity in gerbils.