G
Gyorgy Bagdy
Researcher at Semmelweis University
Publications - 291
Citations - 8390
Gyorgy Bagdy is an academic researcher from Semmelweis University. The author has contributed to research in topics: Migraine & Anxiety. The author has an hindex of 49, co-authored 269 publications receiving 7636 citations. Previous affiliations of Gyorgy Bagdy include National Institutes of Health & Hungarian Academy of Sciences.
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Journal ArticleDOI
Serotonin and epilepsy
TL;DR: Imaging data and analysis of resected tissue of epileptic patients, and studies in animal models all provide evidence that endogenous 5‐HT, the activity of its receptors, and pharmaceuticals with serotonin agonist and/or antagonist properties play a significant role in the pathogenesis of epilepsies.
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NO-induced migraine attack: strong increase in plasma calcitonin gene-related peptide (CGRP) concentration and negative correlation with platelet serotonin release.
Gabriella Juhasz,Terezia Zsombok,Edit A. Modos,Sarolta Olajos,Balázs Jakab,József Németh,János Szolcsányi,József Vitrai,Gyorgy Bagdy +8 more
TL;DR: The fact that plasma CGRP concentration correlates with the timing and severity of a migraine headache suggests a direct relationship between C GRP and migraine, and serotonin release from platelets does not provoke migraine, it may even counteract the headache and the concomitant CGRp release in this model.
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Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression
Robert Culverhouse,Nancy L. Saccone,Amy C. Horton,Yinjiao Ma,Kaarin J. Anstey,Tobias Banaschewski,Margit Burmeister,Sarah Cohen-Woods,Bruno Etain,Helen L. Fisher,Noreen Goldman,Sébastien Guillaume,Sébastien Guillaume,John Horwood,Gabriella Juhasz,Kathryn J. Lester,Laura Mandelli,Christel M. Middeldorp,Emilie Olié,Emilie Olié,Sandra Villafuerte,Tracy Air,Ricardo Araya,Lucy Bowes,Richard Burns,Enda M. Byrne,Carolyn Coffey,William L. Coventry,Katerina A.B. Gawronski,Dana A. Glei,Alex Hatzimanolis,J-J Hottenga,Isabelle Jaussent,Catharine Jawahar,Christine Jennen-Steinmetz,John Kramer,Mohamed Lajnef,Keriann Little,H. M. Zu Schwabedissen,Matthias Nauck,Esther Nederhof,Peter Petschner,Wouter J. Peyrot,Christian Schwahn,Grant C.B. Sinnamon,David Stacey,Y. Tian,Catherine Toben,S Van der Auwera,Nicholas W.J. Wainwright,J. C. Wang,Gonneke Willemsen,Ian M. Anderson,Volker Arolt,Cecilia Åslund,Gyorgy Bagdy,Bernhard T. Baune,Frank Bellivier,Dorret I. Boomsma,Philippe Courtet,Philippe Courtet,Udo Dannlowski,E.J.C. de Geus,John Francis William Deakin,Simon Easteal,Thalia C. Eley,David M. Fergusson,Alison Goate,Xenia Gonda,Hans-Jörgen Grabe,C. Holzman,Eric O. Johnson,Martin A. Kennedy,Manfred Laucht,Nicholas G. Martin,Marcus R. Munafò,Kent W. Nilsson,Albertine J. Oldehinkel,Craig A. Olsson,Johan Ormel,Christian Otte,George C Patton,Brenda W.J.H. Penninx,Karen Ritchie,Marco Sarchiapone,J. M. Scheid,Alessandro Serretti,Jan Smit,Nicholas C. Stefanis,P. G. Surtees,Henry Völzke,Maxine Weinstein,Mary A. Whooley,John I. Nurnberger,Naomi Breslau,Laura J. Bierut +95 more
TL;DR: If an interaction exists in which the S allele of 5-HTTLPR increases risk of depression only in stressed individuals, then it is not broadly generalisable, but must be of modest effect size and only observable in limited situations.
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Anxiety-like effects induced by acute fluoxetine, sertraline or m-CPP treatment are reversed by pretreatment with the 5-HT2C receptor antagonist SB-242084 but not the 5-HT1A receptor antagonist WAY-100635.
TL;DR: The results suggest that increased anxiety in rodents, and possibly, also in humans (e.g. agitation or jitteriness after SSRIs and panic after m-CPP), caused by acute administration of SSRI antidepressants or m- CPP, are mediated by activation of 5-HT2C receptors.
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Effects of serotonergic agonists and antagonists on corticotropin-releasing hormone secretion by explanted rat hypothalami
Aldo E. Calogero,Renato Bernardini,Andrew N. Margioris,Gyorgy Bagdy,William T. Gallucci,Peter J. Munson,Lawrence Tamarkin,Thomas P. Tomai,Linda S. Brady,Philip W. Gold,George P. Chrousos +10 more
TL;DR: The findings suggest that serotonin stimulates CRH secretion by explanted rat hypothalami and that this effect appears to be mediated mainly through a 5HT2 receptor mechanism.