D
Da-Wei Gong
Researcher at University of Maryland, Baltimore
Publications - 66
Citations - 6732
Da-Wei Gong is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Adipose tissue & Alanine transaminase. The author has an hindex of 31, co-authored 63 publications receiving 6162 citations. Previous affiliations of Da-Wei Gong include National Institutes of Health & Veterans Health Administration.
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Journal ArticleDOI
Uncoupling Protein-3 Is a Mediator of Thermogenesis Regulated by Thyroid Hormone, β3-Adrenergic Agonists, and Leptin
TL;DR: UCP3 levels were greatly increased by treatment with the β3-adrenergic agonist, CL214613, suggesting another pathway for increasing thermogenesis and UCP3 mRNA levels were also regulated by dexamethasone, leptin, and starvation, albeit differently in muscle and brown adipose tissue.
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Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action
Rongze Yang,Mi-Jeong Lee,Hong Hu,Jessica Pray,Hai-Bin Wu,Barbara C. Hansen,Alan R. Shuldiner,Susan K. Fried,John C. McLenithan,Da-Wei Gong +9 more
TL;DR: Central obesity is more closely associated with insulin resistance, type 2 diabetes, and cardiovascular disease than is peripheral obesity, but the underlying mechani... as discussed by the authors showed that central (visceral) obesity is associated with Type 2 diabetes.
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Omentin Plasma Levels and Gene Expression Are Decreased in Obesity
Celia M. De Souza Batista,Rong Ze Yang,Mi-Jeong Lee,Nicole M. Glynn,Dao Zhan Yu,Jessica Pray,Kelechi Ndubuizu,Susheel P. Patil,Alan L. Schwartz,Mark D. Kligman,Susan K. Fried,Susan K. Fried,Da-Wei Gong,Alan R. Shuldiner,Alan R. Shuldiner,Toni I. Pollin,John C. McLenithan,John C. McLenithan +17 more
TL;DR: Omentin 1 and omentin 2 gene expression were decreased with obesity and were highly correlated with each other in visceral adipose tissue as mentioned in this paper, indicating that decreased Omentin levels are associated with increasing obesity and insulin resistance.
Journal ArticleDOI
Lack of obesity and normal response to fasting and thyroid hormone in mice lacking uncoupling protein-3.
Da-Wei Gong,Shadi Monemdjou,Oksana Gavrilova,Lisa R. Leon,Bernice Marcus-Samuels,Chieh J. Chou,Carrie Everett,Leslie P. Kozak,Cuiling Li,Chu-Xia Deng,Mary-Ellen Harper,Marc L. Reitman +11 more
TL;DR: The phenotype of UCP1/UCP3 double knockout mice was indistinguishable fromUcp1 single knockout mice, suggesting that UCP3 is not a major determinant of metabolic rate but, rather, has other functions.
Journal ArticleDOI
Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria
Hong Wang,Urmilla Sreenivasan,Hong Hu,Andrew J. Saladino,Brian M. Polster,Linda M. Lund,Da-Wei Gong,William C. Stanley,Carole Sztalryd +8 more
TL;DR: Results suggest that Plin5 regulates oxidative LD hydrolysis and controls local FA flux to protect mitochondria against excessive exposure to FA during physiological stress.